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Sclerotherapy for hemorrhoidal disease: Recent evolutions of an oldies goldy.
World J Gastroenterol
February 2025
Department of General Surgery, Azienda Sanitaria Locale (ASL) Lecce, Casarano 73042, Lecce, Italy.
Treatments for low degree hemorrhoids (I-III degree) are numerous and so are their counterparts for higher degrees. These treatments present nebulous differences in terms of indications and outcomes among techniques. Methods previously abandoned due to side effects and long-term results have recently rejoined the mainstream due to recent peculiar modifications: Hemorrhoidal sclerotherapy is enjoying a new age of interest due to the use of the foam form of polidocanol, which is more effective than the liquid one.
View Article and Find Full Text PDFPotential benefits of GLP-1 receptor agonist in dialysis patients with type 2 diabetes: the need for comprehensive pharmacokinetic and hemodialysis analyses.
Cardiovasc Diabetol
March 2025
Division of Nephrology, Department of Internal Medicine, National Cheng Kung UniversityHospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
The 2022 KDIGO guideline for diabetes management in patients with chronic kidney disease (CKD) had endorsed the use of GLP-1 receptor agonists (GLP-1RAs) for patients with CKD and type 2 diabetes who did not achieve optimal glycemic target with maximally tolerated metformin and sodium-glucose co-transporter-2 (SGLT-2) inhibitor. Our study revealed the potential benefits of GLP-1RAs in patients with dialysis-requiring acute kidney disease possibly owing to pleiotropic effects of the medicine. Nonetheless, pharmacokinetics and dialysis dose were omitted in our subgroup analyses.
View Article and Find Full Text PDFThe urgent need for implementation science to achieve hepatitis C elimination.
Lancet Gastroenterol Hepatol
March 2025
Centre for Implementation Research, Methodological and Implementation Research Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada; School of Epidemiology and Public Health and School of Psychology, University of Ottawa, Ottawa, ON, Canada.
Long-term clinical impact of angiographic complexity in left main trifurcation percutaneous coronary interventions.
Minerva Cardiol Angiol
February 2025
Department of Cardiovascular Sciences, IRCCS A. Gemelli University Polyclinic Foundation, Rome, Italy.
Background: Current evidence on the long-term outcome and its determinants in patients with unprotected left main trifurcation (LMT) treated with percutaneous coronary intervention (PCI) is based on small-sized studies. We aimed to assess the clinical, anatomical and procedural factors impacting long-term clinical outcomes of patients with LMT treated by PCI.
Methods: We conducted a multicenter retrospective study on consecutive patients with unprotected LMT in stable or acute coronary settings who underwent PCI with drug-eluting-stent implantation.
Sentiment analysis of emoji fused reviews using machine learning and Bert.
Sci Rep
March 2025
Department of Computer Science & Engineering, B. P. Poddar Institute of Management and Technology, Kolkata, 700052, India.
The usage of Natural Language Processing (NLP) technology powered by Artificial Intelligence in processing of customer feedback has helped in making critical decisions for business growth in the aviation sector. It is observed that in many of the cases, emojis and emoticons are found to convey a lot of significant information about the user's opinion or experience regarding a certain product, a service or an event. Consequently, it is very much essential that these emojis/emoticons are considered for processing because they are found to play a vital role in sentiment expression, often conveying more explicit information than the text alone.
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