A 27-year-old patient came to the dermatology outpatient clinic of the Erasmus MC because of progressive swelling, pain, itching and skin lesions of the left foot for two days. The symptoms initially started with erythematous urticarial papules and vesicles. After a day severe swelling of the forefoot, bullae around the toes and several slowly progressive serpiginous plaques developed without systemic complaints. A week before the onset of the symptoms, he had returned from a trip to Colombia. Under the working diagnosis of cutaneous larva migrans, ivermectin 0.2 mg/kg for two consecutive days, clobetasol, cetirizine and local compression therapy were started. Two weeks after the start of the treatment, the patient was symptom-free. The disease is self-limiting. In case of multiple lesions or severe reaction, treatment may be considered.
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J Helminthol
March 2025
Instituto de Ecología, A.C., Xalapa, Veracruz, Mexico.
Gyrodactylidae Cobbold, 1864 is a monophyletic family of hyperviviparous species, with 36 genera and approximately 700 species. Here, we focused on one of these genera - namely Jara & Cone, 1989 - characterizing its morphological variation systematically and testing its phylogenetic position in relation to other genera in the family. We collected and describe two new species of monogenean parasites of infecting Neotropical freshwater catfishes in Mexico.
View Article and Find Full Text PDFFront Immunol
March 2025
Institute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, China.
Background: () is a widely prevalent intracellular parasite that infects almost all warm-blooded animals and causes serious public health problems. The drugs currently used to treat toxoplasmosis have the disadvantage of being toxic and prone to the development of resistance, and the only licensed vaccine entails a risk of virulence restoration. The development of a safe and effective vaccine against is urgently needed.
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March 2025
Division of Malaria Research, Proteo-Science Center, Ehime University, Matsuyama, Japan.
Individuals residing in malaria-endemic regions with high disease transmission can develop semi-immunity within five years of age. Although understanding the target of the IgGs in this age group helps discover novel blood-stage vaccine candidates and serological markers, it has not been well elucidated due to limited accessibility to plasmodial antigens and samples. This study presents the first comprehensive analysis of antibody levels in plasma obtained from Burkinabe children (n=80, aged 0 to 5 years) to 1307 proteins expressed by the eukaryotic wheat germ cell-free system.
View Article and Find Full Text PDFBiosaf Health
December 2024
Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei 230032, China.
Recently, there has been a continuous stream of reports on emerging tick-borne pathogens affecting humans. Qinghai Province, located in the northweastern region, is one of China's major pastoral areas, providing a suitable environment for ticks' survival and transmitting tick-borne pathogens. Here, we collected 560 free-living and parasitic ticks from 11 locations in Qinghai Province using the flag-drag method or tweezers, identifying them as belonging to 4 species of ticks.
View Article and Find Full Text PDFNutrients
February 2025
Laboratório de Bioquímica de Tripanosomatídeos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro 21040-360, Brazil.
Background/objectives: Malnutrition and visceral leishmaniasis are major public health problems that are responsible for millions of deaths across many countries. Leishmaniasis development and progression are associated with the host immune status. In this context, malnutrition can directly affect the course of leishmaniasis, impairing several components of the immune system.
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