Objectives: To determine the prevalence of diabetic retinopathy (DR), retinal vein occlusion (RVO), and retinal artery occlusion (RAO) in a tertiary care hospital in Türkiye.
Materials And Methods: The electronic records of all patients over the age of 18 years admitted to a tertiary care general hospital between January 2022 and January 2024 were retrospectively analyzed. For each of the three diseases, demographic data such as age, sex, and common complications were evaluated.
Results: A total of 140,344 patients were retrospectively analyzed. Of these patients, 44.6% (n=62,575) were male and 55.4% (n=77,769) were female. The number of patients diagnosed with retinal vascular disease was 1,963 and 52.3% (n=1,028) of these patients were female. The prevalence of retinal vascular diseases in the general population was 1.4% (95% confidence interval [CI]: 1.34% to 1.46%). The prevalence of DR, RVO, and RAO was 1.12% (95% CI: 1.07% to 1.18%), 0.27% (95% CI: 0.24% to 0.3%), and 0.01% (95% CI: 0% to 0.01%), respectively. Among these three diseases, DR was statistically more common in women (p=0.048) and RAO in men (p=0.015), while RVO (p=0.079) was not associated with sex. In patients with DR, macular edema was more common in patients older than 50 years, while neovascularization was more common in patients younger than 50 years. The development of macular edema and neovascularization was not associated with sex in patients with these three diseases.
Conclusion: This is the first study to report the demographic data of patients diagnosed with retinal vascular diseases in Türkiye. However, there is a need for nationwide, multicenter, hospital and community-based studies including different geographical regions of Türkiye that examine the data of patients in detail.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866982 | PMC |
http://dx.doi.org/10.4274/tjo.galenos.2025.88262 | DOI Listing |
Diabetologia
March 2025
Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China.
Aims/hypothesis: Signalling pathways that regulate endothelial cell (EC) dysfunction, ischaemia and inflammation play a crucial role in retinal microangiopathy such as diabetic retinopathy. MAP4K4 is highly expressed in ECs. However, the involvement of MAP4K4 in retinal vasculopathy of diabetic retinopathy remains unclear.
View Article and Find Full Text PDFTransl Vis Sci Technol
March 2025
Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Purpose: This study aimed to investigate the effects of extraocular muscle recession performed as part of strabismus surgery on posterior retinal and choroidal blood flow.
Methods: A single-center prospective study was conducted on patients who underwent strabismus surgery. Optical coherence tomography, optical coherence tomography angiography, and laser speckle flowgraphy of the macula were performed before surgery and at one week, one month, and four months after surgery.
Transl Vis Sci Technol
March 2025
Ophthalmology Department, Dijon University Hospital, Dijon, France.
Purpose: To compare automated and semiautomated methods for the measurement of retinal microvascular biomarkers: the automated retinal vascular morphology (AutoMorph) algorithm and the Singapore "I" Vessel Assessment (SIVA) software.
Methods: Analysis of retinal fundus photographs centered on optic discs from the population-based Montrachet Study of adults aged 75 years and older. Comparison and agreement evaluation with intraclass correlation coefficients (ICCs) between SIVA and AutoMorph measures of the central retinal venular and arteriolar equivalent, arteriolar-venular ratio, and fractal dimension.
J Glaucoma
March 2025
Department of Ophthalmology, Harvey and Bernice Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR.
Precis: In this prospective multicenter study, eyes with primary congenital glaucoma exhibited lower retinal vascular parameters compared to healthy controls, as assessed by optical coherence tomography angiography fractal dimension analysis.
Purpose: To study the retino-choroidal peripapillary microvascular pattern in primary congenital glaucoma (PCG) using fractal dimension (FD) analysis and compare it to healthy controls.
Methods: This was a prospective multicenter comparative study.
Diabetes Metab J
March 2025
R&D, Dompé Farmaceutici SpA, L'Aquila, Italy.
Background: The CXC motif chemokine ligand 8 (CXCL8)-CXC motif chemokine receptor 1/2 (CXCR1/2) axis has been implicated in type 1 diabetes mellitus (T1DM). Its actions on non-immune cells may also contribute to T1DM-associated complications, including painful diabetic peripheral neuropathy (DPN) and diabetic retinopathy (DR).
Methods: We assessed the efficacy of early (4-8 weeks) or late (8-12 weeks) daily ladarixin (LDX) for the treatment of streptozotocin (STZ)-induced T1DM and the related complications of DPN or DR in male rats.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!