Herlyn-Werner-Wunderlich syndrome (HWWS) combined with pelvic mesothelial cyst is a rare condition that can be easily misdiagnosed. Our center presents a case study of this disease to provide clinicians with valuable insights for accurate diagnosis and treatment. A 12-year-old girl initially received a misdiagnosis of left lower abdominal ectopic kidney hydronephrosis based on B-ultrasound and renography due to intermittent abdominal pain. However, surgical exploration revealed the correct diagnosis of HWWS with pelvic mesothelial cyst. Postoperative pathology confirmed the presence of a mesothelial cyst in the pelvis. Once the diagnosis was confirmed, the patient was transferred to an adult gynaecology department for further treatment. Two months later, during follow-up via telephone, it was reported that the patient had successfully recovered after undergoing transvaginal oblique septum resection. This case report provides detailed information on the diagnostic process, treatment procedures, and examination results, serving as a valuable reference for clinical practitioners dealing with HWWS combined with pelvic mesothelial cysts while reducing the risk of misdiagnosis and mistreatment.
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http://dx.doi.org/10.3389/fmed.2025.1513725 | DOI Listing |
Front Med (Lausanne)
February 2025
Department of Urology, Kunming Children's Hospital, Yunnan Province Clinical Research Center for Children's Health and Disease, Kunming, China.
Herlyn-Werner-Wunderlich syndrome (HWWS) combined with pelvic mesothelial cyst is a rare condition that can be easily misdiagnosed. Our center presents a case study of this disease to provide clinicians with valuable insights for accurate diagnosis and treatment. A 12-year-old girl initially received a misdiagnosis of left lower abdominal ectopic kidney hydronephrosis based on B-ultrasound and renography due to intermittent abdominal pain.
View Article and Find Full Text PDFCancer Sci
February 2025
Department of Cancer Cell Research, Sasaki Institute, Sasaki Foundation, Tokyo, Japan.
Peritoneal metastasis, also known as peritoneal dissemination or carcinomatosis, refers to the spread of cancer to the peritoneum that lines the abdominal and pelvic cavities and covers the abdominal organs. Peritoneal metastasis typically occurs in advanced cancers of abdominal origin, most commonly gastrointestinal and gynecological cancers. Conventional chemotherapy has limited efficacy, and no effective molecular-targeted therapy is currently available for peritoneal metastasis.
View Article and Find Full Text PDFInt J Surg Case Rep
January 2025
Department of Visceral and Digestive Surgery, Monastir University Hospital, Monastir, Tunisia.
Introduction And Importance: Peritoneal inclusion cysts (PICs), also known as peritoneal mesothelial cysts, are rare, benign cystic lesions primarily occurring in the abdominopelvic cavity of premenopausal women with histories of pelvic surgery or inflammation. These cysts can present with nonspecific symptoms and may mimic other abdominal pathologies, making diagnosis challenging.
Case Presentation: A 41-year-old male with no significant medical history, who experienced progressive nonspecific abdominal pain over several months.
Int J Gynecol Pathol
December 2024
Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine.
Transitional cell metaplasia (TCM) resembling benign urothelium is commonly seen around the distal fallopian tube and/or neighboring mesothelial surface; however, its histogenesis remains largely unknown. We observed the emergence of a cytokeratin (CK) 17-positive reserve cell layer in early TCM foci beneath the tubal epithelium, leading us to hypothesize that TCM could be derived from reserve cells. To elucidate the histogenetic process of TCM, we analyzed the histomorphologic features and immunoprofiles for CK17, CK5/6, p63, GATA-3, estrogen receptor (ER), and androgen receptor (AR) in TCM foci arising in the tubal epithelium (31 foci) and pelvic mesothelium (35 foci).
View Article and Find Full Text PDFCureus
October 2024
Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Geneva, USA.
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