Objective: Hypoalbuminemia (HA) is a proxy for malnutrition that has been associated with postoperative complications in several surgical subspecialties. This study investigates the association between pre-operative HA and complications following major salivary gland (MSG) resection.
Methods: Patients undergoing outpatient, elective MSG resection were extracted from the 2005 to 2020 National Surgical Quality Improvement Program database. Demographics and comorbidities were compared between HA (preoperative serum albumin < 3.5 g/dL) and non-HA cohorts. To determine associations between albumin status and postoperative complications, univariate and multivariable binary logistic regression analyses were performed.
Results: A total of 5774 patients undergoing MSG resection were included, of which 321 (5.6%) had preoperative HA. HA was associated with older age on univariate analysis (65.2 vs. 60.2 years, < 0.001). Multivariable analysis found HA to be independently associated with any surgical complication (OR 2.03, 95% CI 1.09-3.56, = 0.019) and length of stay (LOS) ≥ 90th percentile (OR 1.58, 95% CI 1.04-2.38, = 0.032).
Conclusion: Preoperative HA may be a poor prognostic factor associated with an increased risk of surgical complications and prolonged LOS among patients undergoing MSG resection.
Level Of Evidence: 4.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863205 | PMC |
| http://dx.doi.org/10.1002/lio2.70107 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Polymorphous Adenocarcinoma: A Cytological Enigma Unveiled Through Uncommon Locations-A Case Study.
Cytopathology
March 2025
Department of Pathology, JIPMER, Puducherry, India.
Introduction: Polymorphous adenocarcinoma (PAC) is a type encountered in minor salivary glands (49%-87%) PAC may occasionally occur in major salivary glands, in particular the parotid gland approximately 3% (range: 0%-9%) of cases. PAC has become a challenging entity for clinicians to diagnose because of the overlap of its clinical and microscopic features with other salivary gland tumours. Fine-needle aspiration (FNA) and core biopsy findings in these tumours are limited.
View Article and Find Full Text PDFRoot Cause Analysis and Risk of Malignancy of Non-Diagnostic Category per the Milan System for Reporting Salivary Gland Cytopathology.
Diagn Cytopathol
March 2025
Department of Pathology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Greenvale, New York, USA.
Introduction: We aim to perform a root cause analysis (RCA) of the non-diagnostic (ND) category of the Milan System for Reporting Salivary Gland Cytopathology.
Methods: The salivary gland fine needle aspiration (FNA) samples with ND diagnosis and corresponding surgical resections from 2013 to 2023, in the age group of 18 years and above, were included in the cohort for RCA. The cytology and surgical resection slides of cases from this RCA cohort were reviewed.
Update on IgG4-related periaortitis/retroperitoneal fibrosis and periarteritis -recent clinical, diagnostic and therapeutic advances.
Semin Arthritis Rheum
February 2025
Department of Hematology and Immunology, Kanazawa Medical University, Kahoku-gun, Japan. Electronic address:
Background: IgG4-related disease (IgG4-RD) is a systemic, chronic immune-mediated inflammatory disorder that, similar to sarcoidosis, can affect various organs and tissues. IgG4-related periaortitis (PAo)/retroperitoneal fibrosis (RPF) is among the five major manifestations of IgG4-RD. Despite introduction of the ACR and EULAR classification criteria for IgG4-RD in 2019, diagnosing IgG4-related PAo/RPF and periarteritis (PA) remains challenging because obtaining biopsies from these lesions is difficult.
View Article and Find Full Text PDFImmunohistochemistry of carbonic anhydrases I, II and VI in the rat lingual serous salivary glands of von Ebner.
Eur J Histochem
January 2025
Oral Pathology Research Laboratory, Department of Veterans Affairs Medical Center, Washington, DC.
Carbonic anhydrase (CA) has been localized to many structures involved in ion transport including the acini and ducts of the major (parotid, sublingual and submandibular) salivary glands of humans and rodents. It also has been localized by enzyme histochemistry and by immunohistochemistry for CA isoenzyme VI (CA VI) to the acini and ducts of rat serous lingual glands of von Ebner. The purpose of this study was to explore the intracellular distribution by cell type of three CA isoenzymes in these glands.
View Article and Find Full Text PDFEffect of Salivary Flow Rate, Particle Size, and Concentration on Sensations and Liking for Fiber-Fortified Beverages.
J Texture Stud
April 2025
Sensory Evaluation Center, The Pennsylvania State University, University Park, Pennsylvania, USA.
Xerostomia (perceived oral dryness) is a common problem in older adults, often due to hyposalivation, which can cause difficulty in eating and swallowing, resulting in insufficient dietary fiber intake. Recent work shows salivary flow rate, particle size, and concentration are major factors for particle perception in beverages. Given that disliking drives non-consumption, here we explore how particle size, concentration, and salivary flow rate may affect liking in a fiber-fortified model beverage.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!