Background: Tuberculous pericarditis begins with fibrinous and hemorrhagic pericarditis, followed by pericardial effusion, then pericardial hypertrophy, which may turn into subacute or chronic stage, and partly develop into pericarditis. Early diagnosis and treatment have very important clinical significance.
Case Summary: We present a case of an 82-year-old man with a known history of hypertension who was admitted for pleural effusion. CT scan of the chest showed findings of pleural effusion. An echocardiographic study during admission revealed a small amount of pericardial effusion (~1.2 cm in thickness). A whole-body positron emission tomography-computer tomography (PET-CT) scan was then performed and showed a slightly increased fluorodeoxyglucose uptake in the entire pericardium considering tuberculosis. He was started on antituberculosis (TB) medications and tolerated them well. Follow-up echocardiographic study showed no re-accumulation of pleural effusion and pericardial fluid.
Conclusion: Transudative-exudative pleural effusion may be one of the clinical manifestations of tuberculous pericarditis. (1) Bilateral leaking pleural effusion may be the early clinical manifestation of tuberculous pericarditis; (2) PET/CT in the diagnosis and efficacy evaluation of tuberculous pericarditis is valuable; and (3) the central venous pressure may be an indicator of choice for treatment of tuberculous pericarditis.
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http://dx.doi.org/10.1111/crj.70055 | DOI Listing |
N Biotechnol
March 2025
The Mina & Everard Goodman Faculty of Life Sciences and the Institute for Nanotechnology and Advanced Materials, Bar Ilan University, Ramat-Gan, Israel. Electronic address:
While biomarker-guided treatments and NGS-based approaches are refining precision medicine, they are not universally applicable. The gap between the genomic characterization of tumors and their functional behavior is becoming increasingly evident. There is an escalating demand for functional assays that can customize cancer treatments for individual patients and bridge this gap.
View Article and Find Full Text PDFEmerg Radiol
March 2025
Department of Internal Medicine, Armed Forces Capital Hospital, Gyeonggi-do, Republic of Korea.
Purpose: To develop of a novel computed tomography (CT) severity score for hemorrhagic fever with renal syndrome (HFRS) and evaluate its correlation with disease severity and adverse outcomes.
Methods: This retrospective study included 37 patients diagnosed with HFRS from January 2012 to December 2023 who had available clinical laboratory and abdominal CT data during the acute phase. The CT severity score (range 0-5) was based on perirenal fat stranding, pararenal fascia thickening, anterior pararenal space fat stranding, ascites, and pleural effusion.
Respir Med Res
February 2025
Microbiology Laboratory, Abderrahmen Mami Pneumology and Phthisiology Hospital, 2080, Ariana, Tunisia; Faculty of Pharmacy, University of Monastir, 5000, Monastir, Tunisia.
Introduction: Pleural infection is a high-mortality disease with a rising incidence in the past two decades. The knowledge of the main causative organisms is an important step for appropriate treatment. This study aims to describe etiologic and antibiotic resistance features of non-tuberculous pleural infections in adults in a tertiary care center specializing in the treatment of respiratory diseases.
View Article and Find Full Text PDFAttenuation values in computed tomography (CT) are used as a diagnostic aid in certain clinical conditions. In our study, we investigated the effectiveness of attenuation values, obtained through the noninvasive method of CT, in determining the type of pleural effusions in the emergency department. Patients who presented to the emergency department with a diagnosis of pleural effusion and underwent thoracentesis within 48 hours between January 1, 2023, and January 1, 2024, were included in the study.
View Article and Find Full Text PDFPediatr Pulmonol
March 2025
Department of Respiratory Medicine, King George's Medical University, Lucknow, India.
Objective: To identify chest X-ray (CXR) characteristic of Pediatric pulmonary drug-resistant tuberculosis (DRTB) in comparison to drug sensitive tuberculosis (DSTB) for early identification and treatment of DRTB.
Methods: This was a prospective cross-sectional study in which CXR patterns of DS and DR patients aged 1 month to 18 years were categorized into different variants including pleural effusion, cavity lesion, hilar or mediastinal lymph node (LN), consolidation, pneumothorax, pericardial effusion, miliary TB, nodular shadow, and collapse. The consensus between the pulmonary physician and radiologist was measured using weighted kappa test.
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