This essay considers the idea of 'representation' and pain in neuroscience, continental philosophy, and analytic philosophy. To do so, it considers two forms of representation: linguistic representation refers to how words stand in for experiences or things, while mental representation involves the mind's internal depiction of external reality. First, I consider how the question of pain may be conveyed as a question of representation through the McGill Pain Quotient. I then turn to phenomenology to consider how pain cuts straight through representation. Pain is simultaneously an extra-mental experience and an introspective phenomenal experience involving the affect of pain and the social expression of that affect. But to illustrate how pain lacks intention, I consider how the term 'representation' in the neuroscience on cognitive empathy for pain obfuscates the affective ontology of pain experiences. Linguistic expression of pain may suggest belief and representational data, while the phenomenological experience centers around the affective and embodied. Ultimately, the response to pain plays out in social acknowledgement, and both linguistic and mental representation offer necessary but insufficient understandings of ethical acknowledgement. To that end, neuroethics can offer naturalist, physicalist grounds to affirm both the analytic and continental theses about pain and language.
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http://dx.doi.org/10.1007/s11017-025-09700-x | DOI Listing |
Scand J Gastroenterol
March 2025
Department of Abdominal surgery, Helsinki University Hospital, Helsinki, Finland.
Objectives: Extracorporeal shock wave lithotripsy (ESWL) with endotherapy (ET) is the first-line treatment in patients with chronic pancreatitis (CP) and main pancreatic duct stone (PDS). Our study aimed to evaluate factors that predict the outcome of ESWL in CP patients with PDS.
Methods: We retrospectively analyzed data of 166 patients with CP and radiopaque PDS.
Acta Otolaryngol
March 2025
Department of Otolaryngology, Toho University Omori Medical Centre, Tokyo, Japan.
Background: Postoperative haemorrhage following palatine tonsillectomy occurs in 5-14% of cases. Since 2021, our department has used knot suturing with 3-0 Vicryl, and from 2023, continuous suturing with the V-Loc closure device to reduce suture time. While knot suturing is reported to reduce postoperative bleeding and pain, no studies have compared outcomes between different suture methods.
View Article and Find Full Text PDFPalliat Support Care
March 2025
Departments of Psycho-oncology, Saitama Medical University International Medical Center, Saitama, Japan.
Objectives: Naldemedine is a peripherally acting μ-opioid receptor antagonist used to treat opioid-induced constipation. As this drug does not cross the blood-brain barrier, it is believed that patients without brain metastases do not experience opioid withdrawal symptoms.
Methods: Here, we experienced a case in which a cancer patient without brain metastasis presented with anxiety and restlessness that was severe enough to interfere with daily life.
Adv Healthc Mater
March 2025
Department of Orthopaedics, Key Laboratory of Structural Malformations in Children of Zhejiang Province, Key Laboratory of Orthopaedics of Zhejiang Province, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Intervertebral disc degeneration (IVDD) is a major cause of low back pain, where oxidative stress and mitochondrial dysfunction are key contributors. Additionally, ferroptosis, an iron-dependent form of cell death, is identified as a critical mechanism in IVDD pathogenesis. Herein, the therapeutic potential of gallic acid (GA)-derived PGA-Cu nanoparticles, enhanced with functional octapeptide (Cys-Lys-His-Gly-d-Arg-d-Tyr-Lys-Phe, SS08) to build the mitochondria-targeted nanoparticles (PGA-Cu@SS08), and embedded within a hydrogel matrix to form a nanocomposite hydrogel, is explored.
View Article and Find Full Text PDFJ Surg Case Rep
March 2025
Urology Department, Mercy University Hospital, Grenville Place, Cork City T12 WE28, Ireland.
Retrocaval ureter (RU) is a rare congenital malformation where the ureteric pathway is altered, passing posteriorly around the inferior vena cava (IVC). Occasionally, this leads to the IVC compressing the ureter, resulting in obstruction. In this report, we discuss a male who presented with severe right-sided flank pain and was otherwise well with no significant medical, urological, or birth history.
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