This study evaluates the clinical outcomes associated with the use of an improved polyetheretherketone (PEEK) cranial plate in cranioplasty surgery. A total of 104 patients were involved, with significant findings revealing a reduced incidence of postoperative adverse reactions in the improved PEEK group (28.85%) compared to the conventional PEEK group (50.00%, P = 0.027). Patient satisfaction rates were markedly higher in the improved PEEK cohort (P < 0.05). Although the medical expenses for the enhanced PEEK group were greater (¥ 144 600 ± 21 200 vs ¥ 127 400 ± 20 100, P < 0.05), there were no notable differences in cerebral blood flow perfusion or survival time between the two groups (P > 0.05). The conclusions indicate that while the enhanced PEEK cranial plates incur higher upfront costs, their benefits in terms of safety and patient satisfaction, along with improved implant stability and bone healing, support their use in clinical practice. Consequently, the upgraded PEEK material is recommended for cranioplasty procedures.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1116/6.0004208 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Regulation of immune microenvironments by polyetheretherketone surface topography for improving osseointegration.
J Nanobiotechnology
March 2025
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Oral Implants, School of Stomatology, The Fourth Military Medical University, Xi'an, 710032, PR China.
Optimizing the immune microenvironment is essential for successful implant osseointegration. In this study, four different nano/microstructures were fabricated on polyetheretherketone (PEEK) substrates by varying the agitation speed during sulfonation to influence osteoimmunomodulation and implant integration. The results indicate that nano/microstructures with minimal dimensions (SP450) inhibit actin polymerization by reducing calcium influx through PIEZO1, activating the anti-inflammatory M2 macrophage phenotype.
View Article and Find Full Text PDFTrends in spinal implant utilization and pricing.
J Craniovertebr Junction Spine
January 2025
Och Spine at Newyork-Presbyterian at the Weill Cornell Medicine, New York, USA.
Introduction: The escalation of United States (U.S.) spine surgery volume has been accompanied by considerable advancements in our understanding of spine physiology and technology.
View Article and Find Full Text PDF3D printed porous PEEK scaffolds with stable and durable gelatin composite hydrogel coating loaded Yoda1 for in vivo osseointegration.
Int J Biol Macromol
March 2025
School of Medicine, Nankai University, Tianjin 300071, China; Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang 050051, China. Electronic address:
Polyetheretherketone (PEEK) has emerged as a promising material for bone substitution; however, its limited osseointegration hinders its clinical applications. This research employs a porous structural design alongside surface modification techniques to improve the osseointegration properties of PEEK. Porous PEEK scaffolds were fabricated via 3D printing technology, followed by the application of a stable coating of Yoda1-loaded methacrylated gelatin (GelMA) on their surfaces.
View Article and Find Full Text PDFLumbar fusion using a carbon-fiber PEEK pedicle screw system combined with a carbon-fiber PEEK TLIF cage: a prospective, multicenter study.
BMC Musculoskelet Disord
March 2025
Orthopedic Department, Spine Section, Hannover Medical School, DIAKOVERE Annastift, Anna-von-Borries-Str. 1-7, 30625, Hannover, Germany.
Background: Carbon-fiber-reinforced polyether ether ketone (CF-PEEK) is a radiolucent, non-metallic implant material used for instrumented lumbar spondylodesis. Clinical studies of pedicle screw systems employing this material, especially for degenerative indications, are scant.
Methods: We conducted a multicenter, prospective clinical study to assess clinical and radiographic outcomes in patients with symptomatic degenerative lumbar disk disease, including degenerative spondylolisthesis treated with a CF-PEEK pedicle screw and a transforaminal lumbar interbody fusion (TLIF) cage system.
Clinical study on the application effect of improved polyetheretherketone cranial plate in cranioplasty.
Biointerphases
January 2025
Department of Neurosurgery, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai 200072, China.
This study evaluates the clinical outcomes associated with the use of an improved polyetheretherketone (PEEK) cranial plate in cranioplasty surgery. A total of 104 patients were involved, with significant findings revealing a reduced incidence of postoperative adverse reactions in the improved PEEK group (28.85%) compared to the conventional PEEK group (50.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!