A retrospective observational study aimed to assess blood calcium levels in children with lower respiratory tract infections (LRTIs) from September 2023 to February 2024. A total of 225 eligible records were evaluated. Calcium deficiency was observed in 44.8% of children, hyperchloremia in 42.6%, and hyperkalemia in 36.8% on admission. The mean age was 16.8 ± 16.2 months, and the mean SpO was 95.8 ± 2.5%. Although the risk of hypocalcemia was slightly higher in nonimmunized subjects (odds ratio = 1.04 [95% confidence interval = 0.59-1.85]), this was not statistically significant ( > .05). A negative correlation between normal calcium levels and body mass ( =-0.295, = .001) suggests that higher body weight is linked to calcium imbalance. Immunization status and developmental history did not significantly affect the risk of hypocalcemia. The study highlights the importance of regular calcium monitoring in pediatric LRTI patients, as hypocalcemia was prevalent, particularly in those with higher body weight.
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Curr Opin Support Palliat Care
March 2025
Wolfson Palliative Care Research Centre, University of Hull, Hull, East Yorkshire, UK.
Purpose Of The Review: This review summarises high-level evidence for fan therapy and adds a commentary on the relatively-neglected question of how to optimise benefits based on qualitative evidence, clinical experience and broader research and theory.
Recent Findings: Recent high-level evidence suggests the fan reduces time to recovery from episodic breathlessness rather than reduces daily levels over a longer period. Lower grade evidence suggests the fan can also help people increase their physical activity.
Am J Respir Crit Care Med
March 2025
University of Iowa, Radiology and Biomedical Engineering, Iowa City, Iowa, United States;
Rationale: Quantifying functional small airways disease (fSAD) requires additional expiratory computed tomography (CT) scan, limiting clinical applicability. Artificial intelligence (AI) could enable fSAD quantification from chest CT scan at total lung capacity (TLC) alone (fSAD).
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Emerg Microbes Infect
March 2025
State Key Laboratory of Drug Regulatory Science, Evaluation of Biological Products, Key Laboratory of Research On Quality and Standardization of Biotech Products, Institute of Biological Products, National Institutes for Food and Drug Control, Beijing, China.
Mucosal immunity is crucial for preventing the infection and transmission of respiratory viruses. Nasal antibody is inversely correlated with a lower risk of infection with respiratory viruses. However, the current reference standard for nasal antibody assessment is serum-based, mainly consisting of monomeric IgG and IgA.
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March 2025
Hospices Civils de Lyon (HCL), Centre National des virus des infections respiratoires, Institut des Agents Infectieux, Laboratoire de Virologie, Lyon, France.
Background: The epidemiology of respiratory viruses and vaccine effectiveness (VE) in the community is not well described. This study assessed VE against a positive test of influenza (VEf) and SARS-CoV-2 (VECov).
Methods: Data from two large networks of community-based laboratories in France were collected during standard of care in the 2023-2024 epidemic season (n = 511,083 RT-PCR tests).
Infez Med
March 2025
Interventional Pulmonologist, Pulmonary and Sleep Associates of Huntsville, Huntsville, AL, USA.
Background: Enterococci are the third most common cause of healthcare-associated infections in the United States, affecting 10-12% of all transplant recipients worldwide. Enterococcal bacteremia complicates the post-transplant recovery and raises mortality to 18%. This study aims to identify factors linked to mortality in hematopoietic stem cell transplant (HSCT) recipients with Enterococcus infection.
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