Pulmonary arteriovenous malformations (PAVMs) are rare vascular malformations of the lungs. Direct communication of pulmonary arteries to pulmonary veins is the defining characteristic allowing venous blood to bypass the pulmonary capillary system and avoiding an efficient oxygenation process. The complexity of the pathology lies not only in the variety of its manifestations, but also in the choice of the most appropriate and effective treatment. We present a case of a complex PAVM associated with a persistent foramen ovale, with stroke as the onset symptom. Despite timely multidisciplinary treatment of the malformation, a potentially fatal pulmonary complication occurred, highlighting the critical importance of early, interdisciplinary management and ongoing follow-up of PAVMs, particularly in preventing life-threatening outcomes.
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http://dx.doi.org/10.3389/fmed.2025.1490820 | DOI Listing |
BMC Neurol
March 2025
State Key Laboratory for Innovation and Transformation of Luobing Theory; Key Laboratory of Cardiovascular Remodeling and Function Research of MOE, NHC, CAMS and Shandong Province; Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China.
Background: Cryptogenic stroke constitutes approximately 40% of ischemic strokes in young adults, imposing a significant socioeconomic burden. However, the source of embolus has been specifically investigated in a few number of studies. In this report, We document the first case of a cryptogenic stroke associated with a pulmonary arteriovenous fistula (PAVF), providing evidence of mural thrombus formation within the PAVF vessel.
View Article and Find Full Text PDFJTCVS Open
February 2025
Division of Cardiothoracic Surgery, Children's Hospital of Philadelphia, Philadelphia, Pa.
Objective: Patients with pulmonary arteriovenous malformations (PAVM) can have significant morbidity and mortality. Surgical resection in isolation or with embolization is reported to treat diffuse-type PAVMs. Herein, we describe outcomes for children and adults for whom PAVMs were managed with elective surgical resection.
View Article and Find Full Text PDFJ Soc Cardiovasc Angiogr Interv
January 2025
Hospital Santa Marta - Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal.
A 70-year-old woman was admitted with heart failure and signs of pulmonary hypertension on echocardiogram. Cardiac catheterization demonstrated postcapillary pulmonary hypertension, elevated cardiac output, and O saturation enrichment. Computed tomography revealed a large arteriovenous fistula between the common iliac artery and vein, which was due to a lumbar disc surgery performed several years prior.
View Article and Find Full Text PDFJACC Case Rep
March 2025
Department of Pediatric Cardiology, Amrita Institute of Medical Sciences, Kochi, India. Electronic address:
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