Research Objectives: to investigate possible links between antibiotic consumption levels, with subsequent improvement of approaches to enhance antibiotic use effectiveness and curb antibiotic resistance growth.
Inclusion Criteria: the inclusion criteria were antibacterial drugs for systemic use.
Materials And Methods: In this study, we selected 2 multidisciplinary hospitals in Almaty. Financial statements for antibacterial drugs from the last two years (2021-2022) were received. The distribution of antibiotics was analyzed using ABC analysis, antibiotic consumption was assessed, and the AWARE classification proposed by WHO was investigated. In modern medicine, antibiotic resistance is becoming a serious problem. Medical hospitals face the challenge of using antibiotics effectively. The study of strategies such as the AWARE Classification (ACCESS, WATCH, RESERVE) and ABC Analysis helps to optimize the use of antibiotics, curb resistance and save resources of medical organizations, ensuring long-term treatment effectiveness and patient satisfaction. Presented by the World Health Organization, the AWARE classification has been in place since 2019. Many countries, including Kazakhstan, have not yet implemented AWaRe. This article highlights the need for an AWaRe tool to ensure optimal antibiotic use and reduce antibiotic resistance.
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Front Public Health
March 2025
Health Services Academy, Islamabad, Pakistan.
Background: Antimicrobial resistance (AMR) occurs when microbes undergo changes that render antimicrobial drugs ineffective against them, resulting in limited, more expensive treatment options, longer hospital stays, and increased mortality rates. No study has estimated the costs related to AMR in hospitals in Pakistan. This study was conducted to determine the financial burden of antimicrobial resistance (AMR) in Pakistan and to compare it with the additional costs incurred by patients who respond well to antimicrobial treatments.
View Article and Find Full Text PDFWorld J Otorhinolaryngol Head Neck Surg
March 2025
Objectives: Enhanced recovery after surgery (ERAS) protocols for endoscopic sinus surgery (ESS) have not been widely implemented, and a critical review of ERAS recommendations and a comprehensive analysis of the supporting literature has not been undertaken. We describe an ESS ERAS protocol including key perioperative interventions for patients undergoing ESS and assess the available evidence.
Data Sources: A search was conducted of all relevant ERAS literature in otorhinolaryngology, anesthesia, and surgery using Medline (via PubMed), and Scopus.
J Colloid Interface Sci
March 2025
School of Civil Engineering and Architecture, East China Jiaotong University, Nanchang 330013, PR China. Electronic address:
Developing low-oxidant, high efficiency catalysts is critical to meet the green-circular goal in water treatments. Heteroatom-doped graphite-based carbon nitride carrier catalysts are among the most promising candidate materials in water purification catalysis. In this research, a bimetallic catalyst (Fe-Cu@SNC), featuring dual reaction centers, was prepared using a mass-producible co-precipitation method.
View Article and Find Full Text PDFPLoS One
March 2025
College of Nursing and Health, Kongju National University, Gongju, Republic of Korea.
Background: The prices of generic drugs in general are known to be higher in Korea than in other countries. However, it remains unknown whether the price levels of generic drugs in Korea relative to other countries can differ by therapeutic class. Therefore, this study compared the prices of generic drugs in four commonly used drug classes in Korea with those in other high-income countries.
View Article and Find Full Text PDFFront Microbiol
February 2025
Department of Biomedical Sciences, Institute of Health, Jimma University, Jimma, Ethiopia.
The COVID-19 pandemic underscored bacterial resistance as a critical global health issue, exacerbated by the increased use of antibiotics during the crisis. Notwithstanding the pandemic's prevalence, initiatives to address bacterial medication resistance have been inadequate. Although an overall drop in worldwide antibiotic consumption, total usage remains substantial, requiring rigorous regulatory measures and preventive activities to mitigate the emergence of resistance.
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