Gels constitute a versatile class of materials with considerable potential for applications in both technical and medical domains. Physicochemical property characterization is a critical evaluation method for gels. Common characterization techniques include pH measurement, structural analysis, mechanical property assessment, rheological analysis, and phase transition studies, among others. While numerous research articles report characterization results, few reviews comprehensively summarize the appropriate numerical ranges for these properties. This lack of standardization complicates harmonized evaluation methods and hinders direct comparisons between different gels. To address this gap, it is essential to systematically investigate characterization methods and analyze data from the extensive body of literature on gels. In this review, we provide a comprehensive summary of general characterization methods and present a detailed analysis of gel characterization data to support future research and promote standardized evaluation protocols.
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http://dx.doi.org/10.3390/pharmaceutics17020249 | DOI Listing |
Adv Healthc Mater
March 2025
Aix Marseille Université, INSERM, SSA, MCT, Marseille, 13385, France.
Efflux-mediated antibiotic resistance poses a significant global threat, affecting diverse bacterial species. Clinicians recognize the danger of efflux mechanisms during antibiotic treatment, yet precise diagnostic tools remain unavailable. The antibiogram currently infers abnormal efflux pump activity in clinical isolates, which is subsequently confirmed through transcriptomic or genomic analysis.
View Article and Find Full Text PDFIran J Pharm Res
November 2024
Department of Pharmaceutics, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
The inefficiency of some medications to cross the blood-brain barrier (BBB) is often attributed to their poor physicochemical or pharmacokinetic properties. Recent studies have demonstrated promising outcomes using machine learning algorithms to predict drug permeability across the BBB. In light of these findings, our study was conducted to explore the potential of machine learning in predicting the permeability of drugs across the BBB.
View Article and Find Full Text PDFFood Sci Nutr
March 2025
Department of Food Science and Technology, Faculty of Science, Engineering and Agriculture University of Venda Thohoyandou South Africa.
Food security is still a significant problem, particularly in less developed nations. Orphan crops, such as finger millet (FM), are essential for meeting dietary and nutritional needs as well as providing a means of livelihood for economies with limited resources in Asia and Africa. Comparing two varieties of FM malt beverages using sorghum grain as an external reference, the research examined the impact of fermentation time on the physicochemical characteristics and phenolic composition of the FM malt beverages.
View Article and Find Full Text PDFFront Med Technol
February 2025
Faculty of Pharmacy, DIT University, Dehradun, India.
Gold nanoparticles (AuNPs) have emerged as a versatile platform in biomedical applications, particularly in drug delivery, cancer therapy, and diagnostics, due to their unique physicochemical properties. This review focuses on the integration of computational methods and artificial intelligence (AI) with nanotechnology to optimize AuNP-based therapies. Computational modeling is essential for understanding the interactions between AuNPs and biological molecules, guiding nanoparticle design for improved targeting, stability, and therapeutic efficacy.
View Article and Find Full Text PDFHeliyon
February 2025
Center of Excellence for Soil and Fertilizer Research in Africa, College of Agriculture and Environmental Science, Mohammed VI Polytechnic University, Benguerir, Morocco.
The research objectives were to determine extent of soil cadmium (Cd) in the major soil types of the Gedeo Zone of Ethiopia thereby assessing the pollution risk on the environmental health. Four profile pits representing Luvisols, Nitisols, Cambisols, and Leptosols, were excavated and soil samples were collected. Total and available Cd, Cu, Zn, and Mn, including other major soil physicochemical properties, were analyzed in the lab.
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