With the continuous increase in bridge lifespans, the rapid check and evaluation of the vertical bearing capacity for the pile foundations of existing bridges have been in greater demand. The usual practice is to carry out compression bearing tests under static loads in order to obtain the accurate ratio of the dynamic to static stiffness. However, it is difficult and costly to conduct in situ experiments for each pile foundation. Herein, a rapid evaluation method to measure the vertical bearing capacity of bridge pile foundations is proposed. Firstly, a 3D-bearing cap-pile group-soil interaction model was established to simulate a bearing test of a pile foundation that was subject to static loads and dynamic loads, and then the numerical results were validated by in situ dynamic and static loading tests on an abandoned bridge pier with the same pile group foundation; the dataset for machine learning was constructed using the numerical results, and finally, the bearing capacity of the pile foundation could be predicted rapidly. The results show the following outcomes: the established numerical model can effectively simulate dynamic and static loading tests of pile foundations; the intelligent prediction model based on machine learning can predict the ratio of static stiffness to dynamic stiffness and can thus rapidly evaluate the vertical residual bearing capacity and the designed ultimate loading capacity, allowing for the nondestructive testing and evaluation of the pile foundations of existing bridges.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11861730 | PMC |
http://dx.doi.org/10.3390/s25041214 | DOI Listing |
Int J Nanomedicine
March 2025
Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, People's Republic of China.
Objective: Photodynamic therapy (PDT) is a promising strategy with significant clinical application potential for tumor treatment. However, the tumor hypoxia and limited efficacy against tumor metastasis present significant limitations in the clinical application of PDT. To alleviate tumor hypoxia for PDT against tumor growth and metastasis, we developed a self-oxygenated immunoliposome by encapsulating the catalase (CAT) within the liposome cavity and loading the photosensitizer chlorin e6 (Ce6) and immunoadjuvant MPLA in the lipid bilayer of the immunoliposome (CAT@LP-Ce6-A).
View Article and Find Full Text PDFWorld J Surg Oncol
March 2025
Department of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Background: Olfactory neuroblastoma (ONB) is a rare malignancy that develops in the nasal cavity, with appendicular skeletal metastases being exceptionally uncommon. We report the case of a middle-aged male with ONB, presenting with an unusual biopsy-confirmed solitary metastasis to the left proximal femur.
Case Presentation: A 33-year-old male was previously diagnosed with olfactory neuroblastoma in the skull base after initial clinical presentation with progressive left-sided nasal obstruction for six months.
Sci Rep
March 2025
College of Special Education, Changchun University, Changchun, 130022, People's Republic of China.
Increasing studies have shown that the efficacy of Weizmannia coagulans in treating various cancers. We recently identified W. coagulans MZY531 with potent cell anti-proliferation and exhibiting apoptosis induction activities against the mouse H22 hepatocellular carcinoma cell line.
View Article and Find Full Text PDFSci Rep
March 2025
College of Jilin Emergency Management, Changchun Institute of Technology, Changchun, 130012, China.
Earthquakes, as one of the common natural phenomena in China, can directly lead to the collapse of buildings and trigger secondary effects such as landslides and tsunamis, often resulting in significant property losses and casualties. Therefore, conducting seismic risk assessments for regions holds great practical significance. Current disaster research typically requires a comprehensive consideration of the probabilities of disaster-causing factors, the instability of disaster-prone environments, and the vulnerability of disaster-bearing entities.
View Article and Find Full Text PDFPLoS One
March 2025
College of Civil Engineering, Taiyuan University of Technology, Taiyuan, China.
Pile foundation is a commonly recognized form of foundation, and earthquakes are a common seismic damage phenomenon. Accidents resulting from reduction in pile bearing capacity due to earthquakes pose a great threat to people's lives and safety. This article investigates the interaction between soil and piles under earthquake action.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!