Semiconductor lasers operating at the 730 nm peak wavelength have diverse applications, including biomedical diagnostics, agricultural lighting, and high-precision sensing. However, quantum well (QW) materials, commonly employed at this wavelength, often fail to simultaneously meet the dual requirements of lattice matching and bandgap alignment. In this study, GaAsP/AlGaInP large strain compensation QW with lattice mismatches of -7.533‱ and 1.112‱ was developed. Strain compensation was utilized to address the lattice mismatch while ensuring lasing action at 730 nm. Based on this, the impact of waveguide design, particularly graded and asymmetric waveguides, on the power output was explored. Additionally, the relationship between the doping profile of the device and lasing efficiency was investigated. The completed 100 μm wide semiconductor edge-emitting laser (EEL) achieved 730 nm continuous wave laser with 1 W output power at 2 A current. This study proposes an approach to enhance the lasing power and optoelectronic conversion efficiency of lasers and provide valuable solutions for their practical applications.
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http://dx.doi.org/10.3390/s25041173 | DOI Listing |
QuANTUM-First (NCT02668653) was a randomized phase 3 trial in newly diagnosed FLT3-ITDQpositive acute myeloid leukemia (AML) patients treated with quizartinib or placebo plus standard induction and consolidation chemotherapy and/or allogeneic hematopoietic cell transplantation (allo-HCT), followed by single-agent maintenance therapy. We evaluated the impact of allo-HCT performed in first complete remission (CR1) or composite CR1 (CRc1) on overall survival (OS), considering treatment randomization. Post-hoc extended Cox regression multivariable analyses were conducted in patients who achieved CR/CRc by the end of induction, including allo-HCT in CR1/CRc1 as a time-dependent variable to identify prognostic and predictive factors for OS.
View Article and Find Full Text PDFProc Combust Inst
July 2024
Department of Mechanical and Aerospace Engineering, University of California, Los Angeles (UCLA), Los Angeles, California, 90095.
A two-dimensional solid-fuel combustion experiment for fire-resistant polymers under forced convective cross-flow was developed to assess burn characteristics and toxicant formation using advanced laser absorption diagnostics that enable in situ species and temperature measurements near the fuel surface. The method was used to examine the thermochemical flow-field structure near the surface of polytetrafluoroethylene (PTFE) exposed to a well-defined solid-fuel pilot flame burning polymethyl methacrylate (PMMA). Infrared diode and quantum cascade lasers were used to probe rovibrational absorption transitions of hydrogen fluoride (HF) and carbon monoxide (CO), respectively, at the exit plane of a heterogeneous cylindrical fuel grain from which temperature and mole fraction could be inferred.
View Article and Find Full Text PDFMaterials (Basel)
February 2025
Centre for Quantum Physics, Key Laboratory of Advanced Optoelectronic Quantum Architecture and Measurement (MOE), School of Physics, Beijing Institute of Technology, Beijing 100081, China.
A topological insulator with large bulk-insulating behavior and high electron mobility of the surface state is needed urgently, not only because it would be a good platform for studying topological surface states but also because it is a prerequisite for potential future applications. In this work, we demonstrated that tin (Sn) or indium (In) dopants could be introduced into a BiSbTeSe single crystal. The impacts of the dopants on the bulk-insulating property and electron mobility of the surface state were systematically investigated by electrical transport measurements.
View Article and Find Full Text PDFInt J Mol Sci
March 2025
Department of Health Sciences and Sport Medicine, Hungarian University of Sports Science, 1123 Budapest, Hungary.
Unaccustomed and/or strenuous eccentric contractions are known to cause delayed-onset muscle soreness. In spite of this fact, their exact cause and mechanism have been unknown for more than 120 years. The exploration of the diverse functionality of the Piezo2 ion channel, as the principal proprioceptive component, and its autonomously acquired channelopathy may bring light to this apparently simple but mysterious pain condition.
View Article and Find Full Text PDFInt J Mol Sci
February 2025
Department of Physics, University of Nebraska at Omaha, Omaha, NE 68182, USA.
Hexagonal BCN (h-BCN), an isoelectronic counterpart to graphene, exhibits chirality and offers the distinct advantage of optical activity in the vacuum ultraviolet (VUV) region, characterized by significantly higher wavelengths compared to graphene nanoflakes. h-BCN possesses a wide bandgap and demonstrates desirable semiconducting properties. In this study, we employ Density Functional Theory (DFT) calculations to investigate the proximity effects of adsorbed h-BCN flakes on two-dimensional (2D) substrates.
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