Detection of Bagaza Virus in Europe: A Scoping Review.

Vet Sci

Animal and Veterinary Research Centre (CECAV), Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal.

Published: February 2025

The Bagaza virus (BAGV) belongs to the genus (Ntaya serocomplex) and emerged in Europe, Spain, in 2010. The natural transmission cycle of this virus is perpetuated by spp. mosquitoes and viraemic birds. The ability of BAGV to cause infection in several game birds from the family Phasianidae has been well-studied. BAGV is antigenically similar to other orthoflaviviruses from the Japanese encephalitis serocomplex, such as the West Nile and Usutu viruses, a circumstance which can lead to cross-reactivity in less specific serological techniques (e.g., ELISA). Severe implications in animal health has already been described, but some aspects of the dynamics of transmission and the limits of zoonotic potential of BAGV still need to be clarified. Further investigation focused on epidemiological surveillance in high-risk areas would be beneficial for prevention and control of new outbreaks. The present study is a systematic review of the BAGV reports in Europe.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11860654PMC
http://dx.doi.org/10.3390/vetsci12020113DOI Listing

Publication Analysis

Top Keywords

bagaza virus
8
bagv
5
detection bagaza
4
virus europe
4
europe scoping
4
scoping review
4
review bagaza
4
virus bagv
4
bagv belongs
4
belongs genus
4

Similar Publications

Detection of Bagaza Virus in Europe: A Scoping Review.

Vet Sci

February 2025

Animal and Veterinary Research Centre (CECAV), Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal.

The Bagaza virus (BAGV) belongs to the genus (Ntaya serocomplex) and emerged in Europe, Spain, in 2010. The natural transmission cycle of this virus is perpetuated by spp. mosquitoes and viraemic birds.

View Article and Find Full Text PDF

Structure-based discovery of dual-target inhibitors of the helicase from bagaza virus.

Int J Biol Macromol

March 2025

Department of Cardiology, the First hospital of Shanxi Medical University, and MOE Key Laboratory of Cellular Physiology at Shanxi Medical University, Taiyuan, China. Electronic address:

Bagaza virus (BAGV) is a mosquito-borne flavivirus and has caused significant avian death in many regions, and also garnered recognition as a significant human pathogen causing diseases like encephalitis. The genome of BAGV encodes ten proteins including three structural proteins and seven nonstructural proteins. The C-terminus of the BAGV NS3 helicase serves as a helicase during BAGV replication, aiding in ATP hydrolysis and unwinding of double-stranded RNA.

View Article and Find Full Text PDF

Exposure to West Nile Virus in Wild Lagomorphs in Spanish Mediterranean Ecosystems.

Zoonoses Public Health

March 2025

Departamento de Sanidad Animal, Grupo de Investigación en Sanidad Animal y Zoonosis (GISAZ), UIC Zoonosis y Enfermedades Emergentes ENZOEM, Universidad de Córdoba, Córdoba, Spain.

Article Synopsis
  • West Nile virus (WNV) is a widespread mosquito-borne virus raising concerns for health in Europe, yet no studies have previously investigated its impact on wild rabbits and hares in Spain.
  • This study examined WNV exposure in 540 wild lagomorphs in Andalusia, revealing 5% tested positive, with 4.8% of wild rabbits and 0.7% of Iberian hares showing antibodies against the virus.
  • The findings mark the first report of WNV exposure in wild rabbits in Spain and Iberian hares globally, suggesting these animals could help monitor the virus's presence in their ecosystems.
View Article and Find Full Text PDF

Re-emergence of Bagaza virus in wild birds from southern Spain.

Vet Microbiol

November 2024

Departamento de Sanidad Animal, Grupo de Investigación en Sanidad Animal y Zoonosis (GISAZ), UIC Zoonosis y Enfermedades Emergentes ENZOEM, Universidad de Córdoba, 14014 Córdoba , Spain; CIBERINFEC, ISCIII - CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, 28029 Madrid, Spain.

Bagaza virus (BAGV; Orthoflavivirus bagazaense) is an emerging vector-borne flavivirus affecting avian species with severe implications for animal health, and whose zoonotic potential has also been suggested. The aim of the present study was to monitor the epidemic outbreak of BAGV in wild birds from Spain in 2021. BAGV cases were confirmed in game bird species, including red-legged partridges (Alectoris rufa) and common pheasants (Phasianus colchicus) from 24 hunting areas.

View Article and Find Full Text PDF

Emergence of Two Different Genotypes of Bagaza Virus (BAGV) Affecting Red-Legged Partridges in Spain, in 2019 and 2021.

Pathogens

August 2024

Centro de Investigación en Sanidad Animal (CISA-INIA), Consejo Superior de Investigaciones Científicas (CSIC), Carretera Algete-El Casar de Talamanca, Km. 8,1, 28130 Valdeolmos, Spain.

Article Synopsis
  • The Bagaza virus (BAGV) is a flavivirus that affects birds and was first identified in Spain in 2010, closely related to a virus from Israel.
  • After some quiet years, BAGV caused significant outbreaks in Spain in 2019 and 2021 among red-legged partridges.
  • Genetic analysis revealed two different BAGV genotypes in these outbreaks, indicating that the virus has been independently introduced into Spain multiple times.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!