The increasing use of computed tomography (CT) scans significantly contributes to population exposure to ionizing radiation. Traditional dose metrics, such as dose-length product (DLP) and effective dose (ED), lack precision in reflecting individual radiation exposure. This study introduces a novel parameters such as size-specific effective dose (EDss) and the size-specific dose-length product (DLPss), to improve patient-specific dose estimation. The aim of this study is to enhance dose calculation accuracy, optimize CT protocols, and guide the development of next-generation CT technologies. A retrospective analysis of 247 abdominal and pelvic CT scans (113 women, 134 men) was conducted. Anthropometric parameters, including body mass index (BMI), cross-sectional dimensions, and dose indices, were measured. EDss and DLPss were calculated using size-specific correction factors, and statistical correlations between these parameters were assessed. The mean BMI was 25.92 ± 5.34. DLPss values ranged from 261.63 to 1217.70 mGy·cm (mean: 627.83 ± 145.32) and were roughly 21% higher than traditional DLP values, with men showing slightly higher mean values than women. EDss values ranged from 6.65 to 15.45 mSv (mean: 9.42 ± 2.18 mSv), approximately 22% higher than traditional ED values, demonstrating improved individualization. Significant correlations were observed between BMI and effective diameter (r = 0.78), with stronger correlations in men (r = 0.85). The mean CTDIvol was 11.37 ± 3.50 mGy, and SSDE averaged 13.91 ± 2.39 mGy. Scan length reductions were observed in 53.8% of cases, with statistically significant differences by gender. EDss and DLPss offer improved accuracy in radiation dose estimation, addressing the limitations of traditional methods. Their adoption into clinical protocols, supported by AI-driven automation, could optimize diagnostic safety and significantly reduce radiation risk for patients. Further multicenter studies and technological advancements are recommended to validate these metrics and facilitate their integration into daily practice.
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http://dx.doi.org/10.3390/jcm14041348 | DOI Listing |
Acad Radiol
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Department of Nuclear Medicine, Beijing Luhe Hospital, Capital Medical University, Xinhua Road 82, Tong Zhou District, 101199 Beijing, China.
Rationale And Objectives: The objective of this research is to carry out a systematic review and meta-analysis to detect the diagnostic efficacy of 68Ga-FAPI Positron Emission Tomography (PET) Computed Tomography/Magnetic Resonance (CT/MR) in total of the lesions as well as different aspects of metastasis in individuals with ovarian cancers (OC).
Materials And Methods: The PubMed, Embase, Cochrane library, and Web of Science databases were thoroughly searched until the cut-off date of July 23, 2024. The assessment of 68Ga-FAPI PET CT/MR of OC was presented by the included studies.
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