Background: Hemorrhoidal disease is a common anorectal condition characterized by the enlargement and distal displacement of the typical vascular structures in the anal canal. The relationship between DM, lipid metabolism, and hemorrhoidal disease remains underexplored. This study aims to investigate the prevalence of hemorrhoids and the association between glycemic control and lipid profile in diabetic patients.
Methods: This retrospective cross-sectional study included 752 patients who underwent colonoscopy at Erzurum Regional Training and Research Hospital between June 2021 and August 2024. The study population comprised 452 patients with type 2 diabetes mellitus (mean age 63.4 ± 11.0) and 300 nondiabetic patients (mean age 62.8 ± 10.8). The presence of hemorrhoids was confirmed through colonoscopy. Glycemic control parameters, lipid profile, and other biochemical parameters were analyzed.
Results: Hemorrhoids were found in 47.3% ( = 214) of diabetic patients and 17.3% ( = 52) of nondiabetic patients, indicating a significantly higher prevalence in the diabetic group (OR = 4.3, CI = 3.0-6.2, < 0.001). Diabetic patients with hemorrhoids had significantly higher mean HbA1C (8.1 ± 2.1 vs. 7.5 ± 1.8, < 0.001), low-density lipoprotein ( < 0.001), and triglyceride levels ( = 0.005) compared to those without hemorrhoids. Additionally, a longer duration of diabetes and higher hypertension prevalence were observed in the hemorrhoid group.
Conclusions: The findings suggest that poor glycemic control and dyslipidemia are significantly associated with an increased prevalence of hemorrhoids in diabetic patients. These results highlight the importance of comprehensive management of diabetes, including lipid control, to potentially reduce the risk of hemorrhoidal disease.
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http://dx.doi.org/10.3390/life15020178 | DOI Listing |
Endoscopy
March 2025
Department of Gastroenterology and Hepatology, UZ Leuven, Leuven, Belgium.
Single-wavelength endoscopy (SWE) has shown promising results in assessing histological disease activity in ulcerative colitis. Our objective was to validate the real-time performance of a bedside prototype of SWE computer-aided diagnosis (CAD) as proof of concept.A bedside module for real-time use evaluated histological disease activity when endoscopy was performed in the rectum and sigmoid based on white-light endoscopy and SWE (410 nm monochromatic light).
View Article and Find Full Text PDFMycoses
March 2025
Department of Infection Control and Preparedness, Norwegian Institute of Public Health, Oslo, Norway.
Background: Candida auris is an emerging fungal pathogen that is often multidrug-resistant. It can persist on skin and in hospital environments, leading to outbreaks and severe infections for patients at risk. Several countries and institutions are working on establishing guidelines and recommendations for prevention.
View Article and Find Full Text PDFObjective: To analyze the effects of multiplane reconstruction (MPR) technology with multi-slice spiral CT (MSCT) in the etiological diagnosis of acute intestinal obstruction (AIO). Obtaining clear images is of great help in determining the type and etiology of AIO, and doctors can quickly develop treatment plans to improve prognosis and efficacy.
Methods: The clinical data of patients with suspected AIO admitted to our hospital from May 2020 to May 2022 were retrospectively selected as the observation objects.
Sci Data
March 2025
Medical AI Lab, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, 518060, China.
Inflammatory bowel disease (IBD) is a recurrent bowel disease that usually requires magnetic resonance enterography (MRE) for diagnosis and monitoring. However, recognition of bowel segments from MRE images by a radiologist is challenging and time-consuming. Deep learning-based medical image segmentation has shown the potential to reduce manual effort and provide automated tools to assist in disease management; however, it requires a large-scale fine-annotated dataset for training.
View Article and Find Full Text PDFCancer
March 2025
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Background: Oral microbes detected in feces have been associated with colorectal cancer (CRC) in cross-sectional studies. This study investigated the prospective associations between the oral microbiome and incident CRC in the Agricultural Health Study (AHS), National Institutes of Health-AARP (NIH-AARP) Diet and Health Study, and Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial.
Methods: Individuals with oral samples collected before incident CRC diagnoses were identified in the AHS (N = 331), NIH-AARP (N = 249), and PLCO (N = 446) and compared with referent subcohorts (N = 3431).
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