Nanomedicine and Its Role in Surgical Wound Infections: A Practical Approach.

Bioengineering (Basel)

R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

Published: January 2025

Surgical wound infections are a major cause of postoperative complications, contributing to surgical morbidity and mortality. With the rise of antibiotic-resistant pathogens, it is crucial to develop new innovative wound materials to manage surgical wound infections using methods that facilitate drug delivery agents and rely on materials other than antimicrobials. Nanoparticles, in particular, have captured researchers' interest in recent years due to their effectiveness in wound care. They can be classified into three main types: inorganic nanoparticles, lipid-based nanoparticles, and polymeric nanoparticles. Several studies have demonstrated the effectiveness of these new technologies in enhancing wound-healing times and reducing bacterial burden. However, further research is essential to thoroughly evaluate the safety and toxicity of these materials before they can be integrated into routine surgical practice.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11852320PMC
http://dx.doi.org/10.3390/bioengineering12020137DOI Listing

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