A growing body of evidence emphasizes the role of glycemic variability (GV) in the development of conventional diabetes-related complications. Furthermore, advancements in diabetes management and increased life expectancy have led to the emergence of new complications, such as cancer, liver disease, fractures, infections, and cognitive dysfunction. GV is considered to exacerbate oxidative stress and inflammation, acting as a major mechanism underlying these complications. However, few reviews have synthesized the association between GV and these emerging complications or examined their underlying mechanisms. Hence, this narrative review provides a comprehensive discussion of the burden, risks, and mechanisms of GV in these complications, offering further evidence supporting GV as a potential therapeutic target for diabetes management.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11853042 | PMC |
| http://dx.doi.org/10.3390/biom15020188 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Reversing Glycation with a Dietary Supplement Containing Rosemary Extract.
J Clin Aesthet Dermatol
February 2025
Dr. Valacchi is with North Carolina State University, Plants for Human Health Institute in Kannapolis, North Carolina; Kyung Hee University Department of Food and Nutrition in Seoul, Korea; and University of Ferrara Department of Environment and Prevention Science in Ferrara, Italy.
Objective: The authors sought to explore the skin deglycation ability of rosemary extract dietary supplements to support skin health and improve the signs of skin aging.
Methods: A PubMed literature search for English-language articles on rosemary extract effects on glycation and skin aging in clinical and/or preclinical settings was conducted.
Results: Endogenous and exogenous glycative stress and reactive oxygen species lead to the accumulation of advanced glycation endproducts (AGEs), accelerating skin aging.
Patterns of Use of e-Cigarettes and Their Respiratory Effects: A Critical Umbrella Review.
Tob Use Insights
March 2025
Center for the Acceleration of Harm Reduction, University of Catania, Catania, Italy.
E-cigarettes (ECs) are a well-established consumer product. To study their respiratory health effects, there is the issue of heterogenous patterns of use: concurrently with cigarette smoking (dual use), exclusive use after smoking cessation (exclusive use), or use initiated without any prior or current use of cigarettes (naïve use). Our primary goal was to synthesize the evidence on the respiratory effects of ECs use in adults, categorized by their pattern of use.
View Article and Find Full Text PDFPerspectives on access to imaging digital health records in oncology: A mixed methods systematic review.
Health Policy Technol
November 2024
Department of Medical Oncology, ErasmusMC Cancer Institute, Erasmus University Medical Center, Rotterdam, the Netherlands.
Background: Digital Health Records (DHR) have become essential for managing patient data, including radiology and nuclear medicine reports. The wider adoption of DHR globally presents an opportunity to improve patient engagement and empowerment through effective access and sharing of imaging investigations. This review aims to synthesize literature on views, experiences, expectations, and preferences of oncology patients and healthcare professionals (HCP) when accessing imaging via DHR.
View Article and Find Full Text PDFMaternal and fetal outcomes in gestational diabetes mellitus: a narrative review of dietary interventions.
Front Glob Womens Health
February 2025
Department of Nutrition & Dietetics, Symbiosis School of Culinary Arts & Nutritional Sciences, Symbiosis International (Deemed) University, Pune, Maharashtra, India.
Introduction: Gestational diabetes mellitus (GDM) is associated with a myriad of maternal and fetal complications that severely compromise the mother and child's future health. Dietary interventions are effective in reducing the risk of GDM. However, when diagnosed with GDM in 2nd and 3rd the effectiveness of these interventions on maternal and fetal health remains unexplored.
View Article and Find Full Text PDFExploring the impact of equipment modifications on novice tennis players: a scoping review.
Front Psychol
February 2025
Department of Physical Education and Sport, University of Valencia, Valencia, Spain.
Tennis equipment modifications, such as smaller rackets and low-compression balls, are increasingly being used because they can better align with beginners' physical capabilities, enhancing learning and engagement. This scoping review aimed to map current research on equipment modifications for beginner tennis players, identifying how these modifications impact skill acquisition, game performance, biomechanical variables, psychological aspects, and coaches' perspectives. Searches across the Web of Science, Scopus, PubMed, and SPORTDiscus, along with expert input following the PRISMA procedures, yielded 35 studies.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!