A 57-year-old man was admitted to the hospital with recurrent pain in the lower abdomen for more than half a month. Computed tomography urography and MRI of the prostate gland suggested neoplastic lesions in bilateral seminal vesicle glands. An 18F-FDG PET/CT examination revealed multiple hypermetabolic nodules and masses in the prostate and bilateral seminal vesicle gland area. Later histopathology confirmed Waldenström macroglobulinemia with bilateral seminal vesicle gland involvement.
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