To evaluate the improvement effect of ergonomics in the assembly position of an automotive parts production company. From February to December 2023, the assembly positions and 8 operators of an automobile brake parts production company were selected as the research objects. The Swedish Ergonomic Hazard Identification Method and rapid upper limb assessment (RULA) were used to identify and evaluate the adverse ergonomic factors of work-related musculoskeletal disorders (WMSDs) in different parts of the body before and after the improvement. Through field investigation, observation and personnel interviews, three ergonomic problems were identified that need to be solved, namely, the height of the assembly table did not match the height of the operator, the storage space for small accessories was not set reasonably, and empty boxes were difficult to be placed. Technical improvements were made by designing an adjustable height assembly table, improving the layout of the workbench, and designing a mechanical pedal automation device. Statistical analysis was performed by -test and paired rank sum test to evaluate the effectiveness of ergonomic improvements. The operation of the assembly position could be divided into 13 actions, and the time to complete 1 cycle was (83.0±2.7) s. The Swedish Ergonomic Hazard Identification Method identified 28 adverse ergonomic factors of WMSDs in different parts before improvement, and 15 adverse ergonomic factors after improvement. Before ergonomics improvement, the RULA scores were 5 to 7 points, and the risk levels of 6 workers were Ⅳ (very high risk) and 2 workers were Ⅲ (moderate risk). After ergonomics improvement, the RULA score was 4 points, and the risk level was reduced to Ⅱ (low risk). Paired rank sum test results showed that there were statistically significant differences in upper arm, A-part (upper arm, lower arm and wrist) exertion and load, A-part muscle use, neck, total score, and risk level before and after improvement (<0.05). Per capita productivity of assembly post was (40.1±1.4) pieces/ (person·hour) before the improvement and (44.0±1.7) pieces/ (person·hour) after the improvement, the difference was statistically significant (=50.35, <0.001) . The ergonomic improvement measures can reduce the adverse ergonomic factors in the assembly position of an automotive parts production company, reduce the risk of WMSDs, and improve the production efficiency.
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http://dx.doi.org/10.3760/cma.j.cn121094-20240418-00171 | DOI Listing |
Biochemistry
March 2025
Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India.
Base editing is a common mechanism by which organisms expand their genetic repertoire to access new functions. Here, we explore the mechanism of tRNA recognition in the bacterial deaminase TadA, which exclusively recognizes tRNA and converts the wobble base adenosine (A34) to inosine. We quantitatively evaluate the dynamics of tRNA binding by incorporating the fluorescent adenine analogue 2-aminopurine (2-AP) at position 34 in the wobble base of the anticodon loop.
View Article and Find Full Text PDFPLOS Glob Public Health
March 2025
Sydney School of Public Health, The University of Sydney, Sydney, New South Wales, Australia.
Global South countries account for two-thirds of WHO Member States and are a crucial voice in negotiating the 'pandemic treaty', which Member States agreed was necessary if the world was to avoid a repeat of the significant inequity that resulted during COVID-19. The negotiation of a pandemic treaty presents an opportunity to recalibrate global health systems and processes for pandemic prevention, preparedness and response. However, for this to eventuate through global solidarity, as many Global South countries have said they expect, then concessions by developed states on issues that they have long protected must occur.
View Article and Find Full Text PDFCurr Biol
March 2025
Department of Biology and Ecology, Faculty of Science, University of Ostrava, Chittussiho 10, 710 00 Ostrava, Czech Republic. Electronic address:
Streptophytes constitute a major organismal clade comprised of land plants (embryophytes) and several related green algal lineages. Their seemingly well-studied phylogenetic diversity was recently enriched by the discovery of Streptofilum capillaum, a simple filamentous alga forming a novel deep streptophyte lineage in a two-gene phylogeny. A subsequent phylogenetic analysis of plastid genome-encoded proteins resolved Streptofilum as a sister group of nearly all known streptophytes, including Klebsormidiophyceae and Phragmoplastophyta (Charophyceae, Coleochaetophyceae, Zygnematophyceae, and embryophytes).
View Article and Find Full Text PDFJ Am Chem Soc
March 2025
Pingyuan Laboratory, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, P. R. China.
Despite the significant potential of photocatalysis as a robust synthetic tool, the high reactivity of radicals often presents challenges in achieving optimal chemoselectivity. In this study, we demonstrate that this inherent limitation can be strategically harnessed for asymmetric photoredox catalysis. By utilizing a chiral catalyst to facilitate kinetic resolution between the two enantiomers of racemic radical intermediates, one enantiomer selectively undergoes the desired transformation, while noncatalytic side reactions deplete the other enantiomer.
View Article and Find Full Text PDFNano Lett
March 2025
Shenzhen Key Laboratory of Sustainable Biomimetic Materials, Guangdong Provincial Key Laboratory of Sustainable Biomimetic Materials and Green Energy, Department of Materials Science and Engineering, Department of Chemistry, Institute of Major Scientific Facilities for New Materials, Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China.
High sensitivity and spatial recognition of pressure sensors are important for application of the sensors in electronic skins, and in situ visualization is a practical and effective approach to identifying pressure information. Here, we present a facial strategy to achieve in situ pressure information recognition that is visible to the naked eye in coloring form by designing an HPO/PVA film with hemispheric microstructures in an integrated electrochromic pressure sensor. The device can be applied for different stress scenarios within the range of 0-250 kPa by adjusting the spacing of hemispheric microstructures and can identify the magnitude, position, shape, and duration of the pressure.
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