Epstein-Barr virus (EBV) affects over 90% of the global population and has been linked to several autoimmune disorders. This report describes a patient with EBV-associated hepatitis who subsequently developed aplastic anaemia, pernicious anaemia and autoimmune thyroiditis. The patient was treated with an immunosuppressive regimen with gradual improvement in his pancytopenia and autoimmune thyroiditis. This report highlights the importance of a comprehensive evaluation and close monitoring of patients presenting with acute or recent EBV infection. Clinicians are urged to recognise autoimmune sequelae, as early intervention can be life-saving.
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http://dx.doi.org/10.1136/bcr-2024-262950 | DOI Listing |
Int J Chron Obstruct Pulmon Dis
March 2025
Real World Data Analytics, Japan Development, GSK, Tokyo, Japan.
Purpose: Following the relatively recent introduction of single-inhaler triple therapies in Japan, this study compared the effectiveness of switching from multiple-inhaler triple therapy (MITT) to once-daily fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) by investigating COPD exacerbations and adherence among patients with chronic obstructive pulmonary disease (COPD) in Japan.
Methods: This retrospective, pre-post cohort study using the Medical Data Vision Co. Ltd database identified patients with ≥1 inpatient diagnosis and/or ≥2 outpatient diagnoses of COPD at age ≥40 years prior to the index date (first/earliest date of single-inhaler FF/UMEC/VI initiation from May 1, 2019-February 28, 2022, following a switch from MITT).
Clin Endocrinol (Oxf)
March 2025
Division of Division of Endocrinology at the University of Texas Medical Branch, Galveston, Texas, USA.
Background: Hypothyroidism, a condition characterized by an underactive thyroid gland, affects millions worldwide, leading to cognitive and metabolic slowdowns. It is most prevalent in women and older adults, with causes including autoimmune thyroiditis, surgical thyroidectomy, and certain medications.
Standard Of Care And Limitations: The standard treatment involves synthetic levothyroxine (LT4) monotherapy, which alleviates symptoms by converting to the active hormone, T3.
Nutrients
March 2025
Department of Neurosciences, Institute of Graduate Studies, Near East University, Mersin 99000, Turkey.
Background/objectives: Hashimoto's thyroiditis (HT) is the most common autoimmune disease which lowers a patient's quality of life. Our study aimed to assess the association between Mediterranean lifestyle and anthropometric measurements in patients with HT.
Methods: This study was conducted with 120 female patients previously diagnosed with HT.
Eur J Med Res
March 2025
Department of Cardiology, Radiology, and Surgery, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Xiangyang, 441000, China.
Objectives: This study aimed to develop a model for predicting peripheral lymph node metastasis (LNM) in thyroid cancer patients by combining enhanced CT radiomic features with machine learning algorithms. It increased the clinical utility and interpretability of the predictions through SHAP (SHapley Additive exPlanation) values and nomograms for model explanation and visualization.
Methods: Clinical and enhanced CT image data from 375 patients with thyroid cancer confirmed by postoperative pathology at Xiangyang No.
Eur J Dent
March 2025
Department of Endodontics and Restorative Dentistry, Faculty of Dental Medicine, University of Rijeka, Rijeka, Croatia.
Objectives: The present study aimed to compare dental, endodontic, and periodontal status in patients with Hashimoto's disease and healthy patients, as well as to disclose the relation between dental variables and Hashimoto's disease.
Materials And Methods: The research included 85 patients affected by Hashimoto's thyroiditis (analyzed group) and 85 healthy patients (control group). The two groups were matched according to age and gender.
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