Unlabelled: Metabolomics is an omics technology that studies the types, quantities, and changes of endogenous metabolic substances in organisms affected by abiotic and biotic factors.
Background/objectives: Based on metabolomics, small molecule metabolites in biological organisms can be qualitatively and quantitatively analysed. This method analysis directly correlates with biological phenotypes, facilitating the interpretation of life conditions. Wheat ( L.) is one of the major food crops in the world, and its quality and yield play important roles in safeguarding food security.
Methods: This review elaborated on the significance of metabolomics research techniques and methods in enhancing wheat resilience against biotic and abiotic stresses.
Results: Metabolomics plays an important role in identifying the metabolites in wheat that respond to diverse stresses. The integrated examination of metabolomics with other omics disciplines provides new insights and approaches for exploring resistance genes, understanding the genetic basis of wheat metabolism, and revealing the mechanisms involved in stress responses.
Conclusions: Emerging metabolomics research techniques to propose innovative avenues of research is important to enhance wheat resistance.
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http://dx.doi.org/10.3390/metabo15020123 | DOI Listing |
mSphere
March 2025
College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.
Unlabelled: The aim of this experiment was to study the effects of herbal preparations on serum metabolites, rumen microorganisms, and their metabolites, and the relationship between them. Hu sheep ram lambs with an average initial weight of (19.57 ± 1.
View Article and Find Full Text PDFInt J Mol Sci
March 2025
College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010010, China.
The average daily gain (ADG) is a critical index for evaluating growth rates in cattle and is closely linked to the economic benefits of the cattle industry. Heredity is one of the factors affecting the daily gain of cattle. However, the molecular mechanisms regulating ADG remain incompletely understood.
View Article and Find Full Text PDFInt J Mol Sci
March 2025
Department of Biomedical Science, CHA University, CHA General Hospital, Seongnam-si 13488, Gyeonggi-do, Republic of Korea.
Recurrent pregnancy loss (RPL) is characterized by the occurrence of three or more consecutive spontaneous pregnancy losses before 20-24 weeks of gestation. Despite significant progress in the investigation of the biological pathways associated with unexplained RPL, the precise molecular mechanisms remain elusive. Recent advances in multi-omics approaches have identified numerous biomarkers that offer potential avenues for understanding the underlying complexities of RPL.
View Article and Find Full Text PDFInt J Mol Sci
February 2025
Laboratory Animal Center, Chongqing Medical University, Chongqing 400016, China.
Inflammatory bowel disease is a risk factor for brain dysfunction; however, the underlying mechanisms remain largely unknown. In this study, we aimed to explore the potential molecular mechanisms through which intestinal inflammation affects brain function and to verify these mechanisms. Mice were treated with multiple cycles of 1% dextran sulfate sodium (DSS) in drinking water to establish a chronic colitis model.
View Article and Find Full Text PDFInt J Mol Sci
February 2025
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China.
Alzheimer's disease (AD) is characterized by progressive cognition and behavior impairments. Diagnosing AD early is important for clinicians to slow down AD progression and preserve brain function. Biomarkers such as tau protein and amyloid-β peptide (Aβ) are used to aid diagnosis as clinical diagnosis often lags.
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