Green seaweed is currently underused compared with other major seaweed types. Many scientists have reported applications of the green seaweed in various fields in recent years, which makes it a candidate for biomass production in industrial biorefineries. contains a unique polysaccharide called ulvan, which is being considered for medicinal and pharmacological applications. Ulvan is a sulfated polysaccharide including rhamnose and glucuronic acid residues, which has a range of bioactivities, including immunomodulatory, antimicrobial, and anticoagulant properties. The biocompatibility of ulvan makes it a versatile candidate for biomaterial design. This review presents an in-depth analysis of the potential applications of ulvan, starting with extraction methods and structural/biological characterization and moving on to biomaterial design. We also highlight the advantages of ulvan over traditional seaweed polysaccharides such as agar, carrageenan, and alginate.
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http://dx.doi.org/10.3390/md23020056 | DOI Listing |
Microb Biotechnol
March 2025
Science Center for Future Foods, Jiangnan University, Wuxi, Jiangsu, China.
Recombinant human haemoglobin (rHb) is a tetramer protein with heme as cofactors, which have extensive applications in the fields of biomaterials and biomedical therapeutics. However, due to the poor structural stability, the dissociation of heme, weak oxygen transport efficiency, and lower activity, the utilisation of rHb is severely limited in artificial oxygen carriers. Herein, based on the novel developed high-throughput screening strategies and semi-rational design, the engineered rHb mutant with strong stability and heme-binding ability was obtained.
View Article and Find Full Text PDFNanomaterials (Basel)
March 2025
Centre of Physics of Minho and Porto Universities (CF-UM-UP), Laboratory for Physics of Materials and Emergent Technologies (LaPMET), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
In recent decades, substantial progress has been made in embedding molecules, nanocrystals, and nanograins into nanofibers, resulting in a new class of hybrid functional materials with exceptional physical properties. Among these materials, functional nanofibers exhibiting ferroelectric, piezoelectric, pyroelectric, multiferroic, and nonlinear optical characteristics have attracted considerable attention and undergone substantial improvements. This review critically examines these developments, focusing on strategies for incorporating diverse compounds into nanofibers and their impact on enhancing their physical properties, particularly ferroelectric behavior and nonlinear optical conversion.
View Article and Find Full Text PDFAdv Mater
March 2025
NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
Overproduction of pathogenic cell-free DNA (cfDNA) and reactive oxygen species (ROS) plays crucial roles in the onset and perpetuation of ulcerative colitis (UC). Inspired by sweeping robots, a magnesium@polylactic acid-glycolic acid copolymer@polyethylenimine (Mg@PLGA@PEI) microswimmer capable of cleaning off deleterious disease triggers along its path of progress is designed. Mg@PLGA@PEI is successfully synthesized by adopting a core-shell structure with a small opening which allows for Mg-water reaction.
View Article and Find Full Text PDFChem Biodivers
March 2025
Dicle University: Dicle Universitesi, Faculty of Science, Diyarbakır, Diyarbakır, TURKEY.
A new delivery system was designed and synthesized to increase the efficiency of Docetaxel. For this aim, γ-Fe2O3 was synthesized in order to give the nanoparticle the ability to be magnetic targeted. It was functionalized with citric acid to prevent clumping and maintain stability.
View Article and Find Full Text PDFTrials
March 2025
Department of Burn and Plastic Surgery, Govt. Kilpauk Medical College, Chennai, Tamil Nadu, India.
Background: Burn wounds are commonly encountered in clinical settings and the management aims at the prevention of mortality and morbidity due to disability. The platelet-rich plasma (PRP) is blood-derived biomaterial that is enriched with growth factors and cytokines that facilitate wound healing. The PRP has proven its efficacy in various other wounds, but its role in post-burn raw areas and graft take has not been validated.
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