: This study aims to investigate the mechanical behavior of titanium (Ti6Al4V) mini-implants (MIs) under varying orthodontic forces using finite element analysis (FEA) and to evaluate their performance and durability under realistic clinical conditions. Optimal orthodontic forces significantly influence the structural integrity and functional longevity of MIs while minimizing adverse effects on surrounding bone tissues. : A commercially available MI (diameter: 2.0 mm, length: 12 mm) was modeled using FEA. The mandible geometry was obtained using computed tomography (CT) scanning, reconstructed in 3D using SpaceClaim software 2023.1, and discretized into 10-node tetrahedral elements in ANSYS Workbench. Material properties were assigned based on the existing literature, and the implant-bone interaction was simulated using a nonlinear frictional contact model. Orthodontic forces of 2 N and 10 N, inclined at 30°, were applied to simulate clinical loading conditions. Total displacement, von Mises stresses, equivalent strains, fatigue life, and safety factors were analyzed to assess the implant's mechanical performance. : At 2 N, the MI demonstrated minimal displacement (0.0328 mm) and sustained approximately 445,000 cycles under safe fatigue loading conditions, with a safety factor of 4.8369. At 10 N, the implant's lifespan was drastically reduced to 1546 cycles, with significantly elevated stress (6.468 × 10 MPa) and strain concentrations, indicating heightened risks of mechanical failure and bone damage. The findings revealed the critical threshold beyond which orthodontic forces compromise implant stability and peri-implant bone health. : This study confirms that maintaining orthodontic forces within an optimal range, approximately 2 N, is essential to prolong MI lifespan and preserve bone integrity. Excessive forces, such as 10 N, lead to a rapid decline in durability and increased risks of failure, emphasizing the need for calibrated force application in clinical practice. These insights provide valuable guidance for enhancing MI performance and optimizing orthodontic treatment outcomes.
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http://dx.doi.org/10.3390/dj13020071 | DOI Listing |
J Dent Res
March 2025
Department of Neural and Pain Sciences, School of Dentistry, University of Maryland Baltimore. Center to Advance Chronic Pain Research, Baltimore, MD, USA.
Multiple sensory afferents, including mechanosensitive and nociceptive nerves, are projected to the periodontium. Peptidergic afferents expressing transient receptor potential vanilloid 1 (TRPV1), a receptor for capsaicin, mediate pain caused by orthodontic forces. However, their role in orthodontic force-induced alveolar bone remodeling is poorly understood as is the contribution of mechanosensitive ion channels such as Piezo2 in nociceptive nerves.
View Article and Find Full Text PDFObjectives: To report the prevalence of pulp stones (PSs) in molars of orthodontically treated patients, investigate the impact of orthodontic treatment (ORT) using clear aligners (CAs) and fixed appliances (FAs) on the development of PSs in molars, and investigate the association between the incidence of PSs during ORT and the studied variables.
Materials And Methods: Pretreatment orthopantomograms (OPGs) of 600 patients were assessed. Of those, posttreatment OPGs of 272 patients were available.
Clin Exp Dent Res
February 2025
Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Objectives: Various attempts have been made to increase the rate of orthodontic tooth movement (OTM). The aim of this study was to determine the effect of different doses of heparin on OTM and paraclinical factors related to bone metabolism in rats.
Methods And Materials: A total of 24 Sprague-Dawley rats were randomly divided into three groups of 8 animals each and injected with 0 (control), 3000, and 6000 U/Kg/d heparin sulfate for 4 weeks.
Mol Biol Rep
March 2025
Orthodontic Department, School of Stomatology, Beijing Stomatological Hospital, Capital Medical University, Fanjiacun Road 9, Fengtai District, Beijing, 100070, China.
During orthodontic treatment, the application of orthodontic forces to the periodontal tissues leads to the activation of osteoblasts and osteoclasts, which in turn induces bone remodelling and tooth movement. Calcium is a biologically essential element that exists in the internal environment and cells as calcium ions(Ca). The concentration of extracellular Ca can affect the activity and function of osteoblasts and osteoclasts, as well as regulate bone remodelling.
View Article and Find Full Text PDFJ Pharm Bioallied Sci
December 2024
Department of Public Health Dentistry, Tirumala Institute of Dental Sciences and Research Centre, Nizamabad, Telangana, India.
Aim: To evaluate the alkaline phosphatase level in gingival crevicular fluid (GCF) at three time points using clear aligners and fixed orthodontic appliances.
Materials And Methods: A prospective randomized controlled trial was conducted in a tertiary care hospital to treat patients with 4-6 mm crowding in their upper front teeth. The study involved 20 patients, with 10 assigned to each group.
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