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End-stage heart failure and heart transplant in cardiac sarcoidosis: a case series.
Eur Heart J Case Rep
December 2024
Heart Failure and Transplant Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138 Bologna, Italy.
Article Synopsis
- - Diagnosing cardiac sarcoidosis (CS) is difficult, often leading to heart transplantation (HT) as the last option, especially when immunosuppressive therapies fail in advanced cases.
- - The case study presents four patients, each with different symptoms and backgrounds, who ultimately required HT for their CS, revealing the condition's complexity and urgency.
- - There are significant mid- and long-term challenges following HT for CS, notably the need for careful management of immunosuppression to prevent rejection and recurrence of sarcoidosis.
Permanent pacemaker implantation for atrioventricular block secondary to acute pancreatitis in a patient affected by panhypopituitarism.
Egypt Heart J
December 2024
Division of Cardiovascular and Perioperative Medicine, Careggi University Hospital, Largo Brambilla 3, 50134, Florence, Italy.
Background: Hypopituitarism may trigger the development of acute pancreatitis (AP) through multiple mechanisms. AP may alter normal intracardiac conduction leading to an atrioventricular block. Due to the lack of similar cases, the correct timing and indication for pacemaker implantation in such a setting are unknown.
View Article and Find Full Text PDFDevelopment and validation of the D-PACE scoring system to predict delayed high-grade conduction disturbances after transcatheter aortic valve implantation.
EuroIntervention
November 2024
Cardiology Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna Policlinico S. Orsola, Bologna, Italy.
Background: New conduction disturbances are frequent after transcatheter aortic valve implantation (TAVI). Refining our ability to predict high-grade atrioventricular block (AVB) occurring later than 24 hours after the procedure would be useful in order to select patients eligible for early discharge.
Aims: This study was designed to identify predictors of high-grade AVB occurring between 24 hours and 30 days after TAVI and to develop and validate a predictive risk score.
Comparing Left Bundle Branch Area vs Right-Ventricular Septal Pacing in High-Degree Conduction Disease After Transcatheter Aortic Valve Replacement: Randomized Trial Study Protocol.
CJC Open
September 2024
Lankenau Institute for Medical Research, Wynnewood, Pennsylvania, USA.
Article Synopsis
- Left bundle branch area pacing (LBBAP) is a new approach to pacing that aims to improve heart function after aortic valve replacement, compared to the traditional right ventricular septal pacing (RVSP).
- The Left Bundle BRAVE study is a clinical trial designed to compare LBBAP and RVSP in patients with severe aortic stenosis and high-degree heart block to see which method better preserves heart function.
- Key outcomes being measured in the study include changes in heart strain and ejection fraction, along with other markers of heart health and patient performance over a 9-month period.
Late complete atrioventricular block after transcatheter perimembranous ventricular septal defect closure with the KONAR-MF™ VSD occluder: a case report and systematic review.
Cardiol Young
October 2024
Paediatric Cardiology, Univ. Lille, CHU Lille, Lille, France.
The soft nitinol KONAR-MF™ ventricular septal defect (VSD) Multifunctional Occluder (MFO) device is increasingly used for transcatheter perimembranous ventricular septal defect closure. We report for the first time a case of delayed complete atrioventricular block with pacemaker implantation 20 months post-procedure. Through a systematic review, the overall rate of persistent complete atrioventricular block was 0.
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