Background: Pott's disease (PD) is an infection of the vertebral bodies due to Mycobacterium tuberculosis. Commonly presenting with back pain, the insidious nature of the disease can result in the development of kyphotic deformities, epidural collections, and neurological dysfunction. The authors describe the case of a 21-year-old male who presented with symptoms of cervical myelopathy and was found to have a kyphotic deformity involving the C5 and C6 vertebrae with epidural extension. The patient was treated with a combined anterior-posterior surgical approach: anteriorly with C5-6 corpectomy and cage placement and posteriorly with C2-T2 instrumentation. The final pathology was positive for M. tuberculosis, and the patient was placed on antibacterial therapy.
Observations: PD often presents late with symptoms that do not match the severity of the radiological spinal deformities. Surgical intervention is warranted in patients with severe deformity, neural element compression, and concordant neurological deficits. A literature review demonstrated that the combined anterior-posterior approach provides the greatest correction of kyphotic deformities. However, both anterior and combined approaches are associated with good outcomes and relatively few surgical complications.
Lessons: The combined anterior-posterior surgical approach for cervical PD is recommended when kyphosis is severe. With appropriate surgical and medical management, most patients recover well without recurrence of symptoms. https://thejns.org/doi/10.3171/CASE24652.
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http://dx.doi.org/10.3171/CASE24652 | DOI Listing |
JACC Cardiovasc Interv
January 2025
Ascension Saint Thomas, Nashville, Tennessee, USA.
Background: Treating anterior and bileaflet mitral valve disease in patients with primary or degenerative mitral regurgitation (DMR) is considered more challenging than posterior leaflet repair.
Objectives: The aim of this analysis was to evaluate the impact of anterior, posterior, or bileaflet disease on outcomes following mitral transcatheter edge-to-edge repair (M-TEER) in the EXPANDed studies.
Methods: EXPANDed is a pooled, patient-level analysis of subjects undergoing M-TEER with the MitraClip G3 or G4 system as part of the contemporary EXPAND and EXPAND G4 studies.
J Neurosurg Case Lessons
March 2025
Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New York.
Background: Bilateral facet dislocation results from flexion and distraction forces that tear the posterior ligamentous complex, disrupt the facet joint capsules, and can cause fracture of the superior articular processes of the facet joints, leading to vertebral subluxation and potentially serious spinal cord injury. When clinically feasible, the typical management is rapid closed reduction followed by fusion, typically by means of anterior, posterior, or circumferential fixation. However, the risk of construct failure in the event of anterior-only fixation is not fully understood.
View Article and Find Full Text PDFHeliyon
February 2025
Department of Physical Therapy and Health Rehabilitation, College of Applied Medical Sciences, Majmaah University, Majmaah, Saudi Arabia.
Aim: This study aimed to identify optimal methods of acceleration analysis to accurately detect dual-task-related changes in walking sway.
Methods: Twenty-six healthy adults participated in this study, undergoing various cognitive dual-task conditions while walking. Accelerometers were attached to the lower back to record center-of-mass (COM) acceleration in anterior-posterior (AP) and mediolateral (ML) directions.
Front Physiol
February 2025
School of College of Art and Physical Education, Hanyang University, Seoul, Republic of Korea.
Background: Dancers face significant physical demands and are at high risk for lower extremity injuries due to the complexity and intensity of their movements, which require strong dynamic balance. Improving dynamic balance through training can potentially enhance performance and reduce injury risk.
Objective: This study aimed to investigate the effects of a 12-week combined balance and plyometric training program (BP) compared to plyometric training alone (PL) on dynamic balance and lower extremity injury risk among college dancers.
Biomedicines
February 2025
Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, KY 40202, USA.
: Preliminary observations support the view that spinal cord epidural stimulation (scES) combined with trunk-specific training can improve trunk stability during functional activities in individuals with thoracic spinal cord injury (SCI). We studied the acute effects of trunk-specific stimulation on sitting postural control. : Twenty-three individuals with severe cervical SCI were implanted with an epidural stimulator.
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