Cocaine abuse poses a significant public health challenge, leading to severe systemic and localized complications. Intranasal cocaine use can result in chronic rhinitis, septal perforation, and palatal perforation due to its vasoconstrictive effects, which cause ischemia and tissue necrosis. We present the case of a 44- year-old woman with a 10-month history of palatal perforation, attributed to 12 years of chronic cocaine use, presented with nasal regurgitation, feeding difficulties, and cachexia. Examination revealed a 3 x 2 cm palatal perforation, nasal asymmetry, and a saddle nose deformity. Computerized tomography scans showed extensive nasal septum perforation and sinus mucosal thickening. Initial treatment involved antibiotics for sinusitis, followed by the fabrication of an obturator prosthesis to improve speech and feeding. The chronicity and extent of the palatal and nasal damage illustrates the severe consequences that can arise from sustained abuse. This case highlights not only the physical manifestations but also the challenges in managing such cases, emphasizing the necessity of a multidisciplinary approach. The integration of dental, otolaryngological, and psychological care is crucial for both immediate and long-term management. The main lesson from this case is the importance of comprehensive, patient-centered care that prioritizes stabilization and quality of life while supporting the patient's path to rehabilitation. Provisional treatment with an obturator prosthesis can provide significant improvement in speech and feeding, providing a viable solution until the patient can maintain abstinence. Conservative management and prosthetic rehabilitation remain effective options, reinforcing the need for individualized, multidisciplinary care strategies.
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http://dx.doi.org/10.5867/medwave.2025.01.3012 | DOI Listing |
Medwave
February 2025
Escuela de Odontología, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago de Chile.
Cocaine abuse poses a significant public health challenge, leading to severe systemic and localized complications. Intranasal cocaine use can result in chronic rhinitis, septal perforation, and palatal perforation due to its vasoconstrictive effects, which cause ischemia and tissue necrosis. We present the case of a 44- year-old woman with a 10-month history of palatal perforation, attributed to 12 years of chronic cocaine use, presented with nasal regurgitation, feeding difficulties, and cachexia.
View Article and Find Full Text PDFZhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
January 2025
Department of Oral and Maxillofacial Surgery, the First Affiliated Hospital of Bengbu Medical University, Bengbu Anhui, 233004, P. R. China.
Objective: To investigate the effectiveness of posterior lateral perforator flap in lower limb combined with free fibula for maxillary tissue defect repair.
Methods: Between December 2018 and December 2023, 16 patients with the maxillary malignant tumors were admitted. There were 10 males and 6 females, with an average age of 64.
Lasers Med Sci
November 2024
Department of Orthodontics, at Institute of Oral Health Science, Ajou University School of Medicine, Suwon, Korea.
Aim: The aim of this study was to evaluate the expression levels of vascular endothelial growth factor (VEGF), Peroxiredoxin 1 (PRX1), glucose transporter 1 (GLUT1) and type I collagen (COL1) and the rate of tooth movement comparing 3 accelerated tooth movement (ATM) methods: Corticopuncture (CP), photobiomodulation (PBM) and the combined technique (CP + PBM) on days 1, 3, 7 and 14.
Methods: Orthodontic tooth movement was induced in 24 male Wistar rats. CP procedure included three perforations: two in the palate and one mesial to the molars.
Cureus
October 2024
Department of Prosthodontics and Crown and Bridge, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, IND.
The outbreak of COVID-19 swept massive masses causing rhinocerebral mucormycosis, a fatal mycotic infection, and high mortality among humans. It affects individuals with weakened immune systems, resulting in severe ulcers on the palate or perforation of the palate, accompanied by blackish necrotic tissue and exposure of underlying bone. Some of the key symptoms include rhinorrhea, facial swelling, pain in the orofacial region, varying degrees of fever, headaches, blurred vision due to proptosis, and involvement of the contents of the orbit.
View Article and Find Full Text PDFCase Rep Dent
October 2024
Centre for Research in Public Health and Clinical Epidemiology (CISPEC), Faculty of Health Sciences Eugenio Espejo, Universidad UTE, Quito, Ecuador.
Root canal perforations are frequent but critical complications in endodontic treatments, which can pose a risk of irreversible damage to the affected tooth. These perforations typically occur during root canal preparation or endodontic post placement, presenting significant therapeutic challenges. The main objective in the management of such complications is to seal the perforation, thus preventing bacterial invasion and tooth loss.
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