Aluminum phosphide (AlP) poisoning typically has a poor prognosis, but this case report from Nepal demonstrated that prompt hospitalization, aggressive supportive care, including gastric lavage with coconut oil, and careful management of metabolic acidosis can lead to successful patient recovery.
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http://dx.doi.org/10.1002/ccr3.70228 | DOI Listing |
Toxicol Rep
June 2025
Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Aluminum phosphide (ALP) poisoning is a crucial health problem owing to its easy availability, extreme potency, and absence of specific treatment modalities. This study aimed to assess the role of the glucose/potassium (Glu-K) ratio in predicting the severity and adverse outcomes of acute ALP poisoning. The current retrospective cohort study involved patients with acute ALP poisoning who were admitted to Tanta University Poison Control Center from June 2022 to June 2024.
View Article and Find Full Text PDFAluminum phosphide (AlP) poisoning typically has a poor prognosis, but this case report from Nepal demonstrated that prompt hospitalization, aggressive supportive care, including gastric lavage with coconut oil, and careful management of metabolic acidosis can lead to successful patient recovery.
View Article and Find Full Text PDFCureus
December 2024
Anesthesia Department, PGY2 Anesthesia, Lady Reading Hospital, Peshawar, PAK.
Background: Acute aluminum phosphide (ALP) poisoning presents a significant global medical challenge, particularly in regions where it is commonly used as a pesticide. Despite medical advancements, mortality rates from ALP poisoning remain high. Glucose-insulin-potassium (GIK) infusion therapy has emerged as a potential treatment for ALP poisoning due to its ability to counteract its toxic effects on metabolism and heart function.
View Article and Find Full Text PDFBMC Pediatr
January 2025
Pediatric Nursing Department, Faculty of Nursing, Benha University, Benha, Egypt.
Toxicol Res (Camb)
February 2025
Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Menoufia University, Yassen Abd Al Ghafar Street, Shibin El-Kom 6132720, Egypt.
Objective: Aluminum phosphide (AP) intoxication is a life-threatening emergency with no available effective antidote. This study evaluated the efficacy and safety of N-acetylcysteine (NAC) infusion in cases of acute AP poisoning.
Methods: This randomized, single-blinded, parallel-group, controlled, clinical trial enrolled 96 patients with acute AP poisoning.
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