A 78-year-old man presented with shortness of breath and lower limb edema. Echocardiogram showed severely decreased biventricular function with a large clot straddling the patent foramen ovale extending from the right atrium into the left atrium and ventricle.
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http://dx.doi.org/10.14797/mdcvj.1532 | DOI Listing |
Front Neurol
February 2025
Catholic Health Initiatives (CHI) Memorial Neuroscience Institute, Morehouse School of Medicine, Chattanooga, TN, United States.
Background: Stroke is the leading cause of adult disability worldwide, with approximately 30% of strokes remaining cryptogenic. One potential important etiology is a patent foramen ovale (PFO), which may contribute to stroke through paradoxical thromboembolism or thromboembolus formation. Recent advancements in robot-assisted transcranial Doppler (raTCD) have shown increased sensitivity in detecting right-to-left shunt (RLS) compared to transthoracic echocardiography (TTE), particularly in detecting the large shunts which are associated with higher stroke risk.
View Article and Find Full Text PDFCureus
February 2025
Department of Cardiology, Henry Ford Providence Hospital, Southfield, USA.
Mitral regurgitation (MR) is a common valvular abnormality in patients in the Western world. Treatment options include surgery and edge-to-edge repair of the mitral valve leaflets using the MitraClip device. However, MR may recur, and MitraClip can be unsuccessful, posing a challenging management dilemma.
View Article and Find Full Text PDFCardiovasc Interv Ther
March 2025
Cardiology Unit, Alessandro Manzoni Hospital, Lecco, Italy.
Circ Cardiovasc Interv
March 2025
Unit of Structural Heart Diseases, First Department of Cardiology, National and Kapodistrian University of Athens, Hippocration General Hospital of Athens, Athens, Greece; First Department of Cardiology, National and Kapodistrian University of Athens, Hippocration General Hospital of Athens, Athens, Greece.
Nickel-containing devices, such as the Amplatzer PFO Occluder and Gore® Cardioform Septal Occluder (GSO), are used for transcatheter patent foramen ovale (PFO) closure. However, the impact of nickel hypersensitivity on post-procedural outcomes remains poorly understood. This study aimed to evaluate the risk of adverse events, in patients with nickel hypersensitivity undergoing PFO closure.
View Article and Find Full Text PDFJACC Case Rep
March 2025
Department of Cardiology, Oxford University Hospitals, Oxford, United Kingdom. Electronic address:
An 82-year-old man developed acute breathlessness and cyanosis, exacerbated while upright and improved on lying flat (platypnea-orthodeoxia syndrome). Echocardiography revealed acute torrential tricuspid regurgitation due to a flail posterior leaflet leading to right-to-left shunting through a patent foramen ovale (PFO). The patient's symptoms resolved after transcatheter PFO closure and tricuspid valve edge-to-edge repair.
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