Cerebral aspergilloma of initial sinus origin developed in a patient with mixed cell leukemia. Computed tomography imaging showed signs of a cystic multitumoral syndrome with a crown-shaped filling image without peritumoral edema. Follow up of cerebral lesions during medical treatment was by repeated CT scans, with progressive regression of images over a period of 8 months. The patient died after recurrence. Aspergilloma is seen mainly in patients with alternating immunity defenses.
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Cureus
August 2024
Respiratory Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.
Cureus
July 2024
Nephrology, Government Kilpauk Medical College, Chennai, IND.
We report a case of an Aspergillus fungal ball in a transplant graft kidney presenting as obstructive nephropathy. This is a rare manifestation considering the usual presentations of Aspergillus infection, which are pulmonary, rhino-cerebral, and disseminated forms. Imaging showed hydronephrosis with an echogenic material in the transplant renal pelvis, which was further found to be the fungal ball.
View Article and Find Full Text PDFPediatr Int
November 2023
Department of Neurosurgery, Beijing Children's Hospital Affiliated to Capital Medical University, National Center for Children's Health, Beijing, China.
Cardiol Young
May 2023
Department of Pathology, Seoul National University Hospital, Seoul, South Korea.
Invasive aspergillosis is a major cause of infectious disease in immunocompromised patients; however, cardiac involvement in pulmonary aspergillosis is not well-known. Two paediatric patients undergoing chemotherapy were diagnosed with cardiac aspergilloma, accompanied by pulmonary aspergillosis. In both patients, antibiotic and antifungal treatments were initiated immediately after the pneumonia was diagnosed; however, both died of multiple cerebral thromboembolisms.
View Article and Find Full Text PDFCureus
June 2022
Radiology, Aga Khan University Hospital, Karachi, PAK.
Radiological presentation of central nervous system (CNS) aspergillosis is variable and depends on the immune status of the patients. Typical features of meningoencephalitis, infarction, abscess, and mycotic aneurysms commonly occur in immunocompromised patients. A rare mass-like or tumoral form of cerebral aspergillosis has been described mostly in immunocompetent patients which results in a diagnostic dilemma, thus potentially causing a delay in the management.
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