One anastomosis gastric bypass (OAGB) has gained popularity and it is currently the third most frequently performed bariatric procedure worldwide. A marginal ulcer (MU) at the anastomosis site between the gastric pouch and the small intestine is a common complication of gastric bypass procedures but a rare complication of OAGB. Risk factors for MUs include cigarette smoking, alcohol misuse, and infection. MU symptoms include abdominal pain, nausea, and vomiting; however, some patients are asymptomatic. MU perforations are repaired as follows: laparoscopy with or without ulcer debridement, omental patch closure, conversion into Y gastric bypass, or reoperation. This report describes MU perforations in two patients after OAGB.
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http://dx.doi.org/10.1093/jscr/rjaf073 | DOI Listing |
J Clin Gastroenterol
March 2025
Department of Gastroenterology and Hepatology, Hackensack Meridian Network, Hackensack, NJ.
Background: EUS-guided gastroenterostomy (EUS-GE) is a minimally invasive therapy for the management of gastric outlet obstruction (GOO). EUS-GE has demonstrated excellent short-term efficacy without the risks of surgical bypass. However, there is limited data on follow-up outcomes.
View Article and Find Full Text PDFInt J Endocrinol Metab
October 2024
Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Context: This paper aims to review the findings of the Tehran Obesity Treatment Study (TOTS) on obesity and bariatric surgery (BS).
Evidence Acquisition: The objective of this review is to assess all aspects of BS in individuals with severe obesity, focusing on research conducted within the TOTS framework.
Results And Conclusions: The TOTS studies have produced significant national-level findings, highlighting critical issues related to the effectiveness and outcomes of bariatric procedures, the importance of comprehensive nutritional management, and the complications associated with these interventions in this population.
Clin Endocrinol (Oxf)
March 2025
Department of Addiction Psychiatry, Taoyuan Psychiatric Center, Ministry of Health and Welfare, Taoyuan City, Taiwan.
Background: Post-bariatric hypoglycemia (PBH) after Roux-en-Y gastric bypass (RYGB) is a complex complication, often characterized by potentially severe hypoglycemic episodes and reduced hypoglycemia awareness. Recent findings suggest that autonomic dysfunction, preoperative hypoglycemia symptoms, and early dumping syndrome may each contribute to PBH risk.
Objective: To discuss critical insights from the recent study by Grover et al.
World J Gastrointest Surg
February 2025
Department of General Surgery, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330000, Jiangxi Province, China.
Background: The efficacy of various bariatric surgeries varies in reducing blood glucose levels. Given the distinct mechanisms and anatomical alterations associated with each procedure, it is crucial to compare their glycemic control outcomes. We hypothesize that proximal small intestinal bypass (PSIB) is superior in blood glucose reduction over Roux-en-Y gastric bypass (RYGB) and jejunoileal bypass (JIB).
View Article and Find Full Text PDFNeurogastroenterol Motil
March 2025
Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Background & Aims: Disorders of gut-brain interaction (DGBI) in obesity could impair health outcomes. Therefore, we aimed to study the prevalence and burden of symptoms compatible with a DGBI in obesity and assess the effect of obesity treatment on comorbid DGBI.
Methods: We used baseline and two-year follow-up data from a prospective non-randomized cohort study including patients with obesity referred for obesity treatment.
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