In the medical literature there are several case reports of physicians who tried to transfer a gestational sac from the fallopian tube to the uterus. In this article, a review of the scientific literature on the subject was conducted and an answer was provided to the question, truth or fiction? Anyone who deals with early pregnancies, understands the complexity of the implantation process during early pregnancy, and that there is no clear anatomical separation plane in early pregnancy, between the decidua and the early placental villi that penetrate it. Several case reports in the medical literature describe a successful transfer of an ectopic pregnancy from the fallopian tube to the uterine cavity. Those case reports are unreliable, and attempts to reproduce them have not been successful. Currently, attempts should not be made to transfer an ectopic pregnancy into the uterine cavity, as they may endanger the patients' lives - primum non nocere.
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Arch Pathol Lab Med
March 2025
From Translational Medicine, ImmunoGen, Inc, Waltham, Massachusetts (Deutschman, Sloss).
Context.—: The VENTANA FOLR1 (FOLR1-2.1) RxDx (FOLR1 CDx) assay, developed by Roche Tissue Diagnostics, is a Food and Drug Administration-approved immunohistochemical assay intended for use in the assessment of folate receptor α (FRα) expression in formalin-fixed, paraffin-embedded epithelial ovarian, fallopian tube, and primary peritoneal tumor specimens.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
February 2025
Pregnancy Loss Research Group, Department of Obstetrics and Gynaecology, University College Cork, Cork, Ireland; Cork University Maternity Hospital, Wilton, Cork, Ireland; National Perinatal Epidemiology Centre, University College Cork, Ireland.
Objective(s): Ectopic pregnancy is where a pregnancy develops in an abnormal location. The incidence of ectopic pregnancy in Ireland is approximately 14.8 per 1,000 maternities.
View Article and Find Full Text PDFCancer Res Commun
March 2025
University of California, Santa Cruz, Santa Cruz, CA, United States.
Ovarian cancer is the sixth leading cause of cancer-related mortality among individuals with ovaries, and high-grade serous ovarian cancer (HGSOC) is the most common and lethal subtype. Characterized by a distinct and aggressive metastatic pattern, HGSOC can originate in the fallopian tube with the transformation of fallopian tube epithelial (FTE) cells, which metastasize to the ovary and subsequently to the omentum and peritoneal cavity. The omentum is a privileged metastatic site, and the metabolic exchange underlying omental metastasis could provide enzyme or receptor targets to block spread.
View Article and Find Full Text PDFInt J Gynecol Cancer
January 2025
Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan; Chang Gung University College of Medicine, Taoyuan City, Taiwan.
Objective: The HALO study (NCT04991051) determined the prevalence of homologous recombination deficiency and its associated factors in patients with high-grade serous/endometrioid ovarian, primary peritoneal, and/or fallopian tube cancers across Asia, the Middle East, and Russia.
Methods: This multinational, cross-sectional, real-world study enrolled adult women with newly diagnosed stage III or IV high-grade serous/endometrioid ovarian, primary peritoneal, and/or fallopian tube cancers. Formalin-fixed paraffin-embedded tumor blocks were collected within 120 days of enrollment.
Turk J Obstet Gynecol
March 2025
University of Arizona, College of Medicine, Phoenix, Arizona, USA.
Although the removal of the adnexa technically removes more tissue, it may require less fine manipulation and dissection than cystectomy. Secondary to this, we sought to measure the effectiveness and safety of laparoendoscopic single-site surgery (LESS) versus conventional laparoscopy (CLS). We search six databases to find studies comparing LESS and CLS for ovarian lesions where removal of the entire ovary, with or without the fallopian tube, is necessary.
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