Unlabelled: Changes in glucose and insulin are potentially involved in the appetite-regulatory effects of exercise considering their role post-prandially.
Purpose: To examine if glucose and insulin play a role in post-exercise appetite regulation.
Methods: 12 participants (M=8; 26±5 y) completed 3 experimental sessions in a systematically rotated randomized crossover design: 1) no-exercise control (CTRL); 2) moderate-intensity continuous training (MICT; 30-min, 70% maximal oxygen consumption (V̇O2max)); and 3) sprint interval training (SIT; 4 x 30-s "all-out" sprints, interspersed with 4-min rest). Plasma glucose, insulin, acylated ghrelin, active peptide tyrosine tyrosine (PYY), active glucagon-like peptide-1 (GLP-1), and overall appetite perceptions were measured pre-exercise, 0-, 30-, 60-, and 120-min post-exercise. Energy intake was recorded the day before, of, and after experimental sessions.
Results: Glucose was elevated 0-min post-exercise (p<0.097, d>0.52) compared to CTRL with no differences between exercise bouts. Acylated ghrelin was suppressed by MICT (60-, 120-min) and SIT (0-, 30-, 60-, 120-min; p<0.080, d> 0.56) compared to CTRL, while also suppressed in SIT compared to MICT at 30-, 60-, 120-min (p<0.026, d>0.74). GLP-1 was elevated following MICT (0-, 30-, 60-min) and SIT (60-min; p<0.094, d>0.53) compared to CTRL and following MICT compared to SIT (0-min; p=0.005, d=1.03). Overall appetite was suppressed by SIT post-exercise (p<0.058, d>0.61) compared to CTRL and MICT, and by MICT 0-min post-exercise compared to CTRL (p=0.036, d=0.71). There were no exercise effects on insulin, PYY, or free-living energy intake (p>0.217, ηp2<0.130).
Conclusion: Glucose and insulin do not appear to play a role in exercise-induced appetite suppression.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1139/apnm-2024-0331 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Oral Lipid-Based Nanomedicine for the Inhibition of the cGAS-STING Pathway in Inflammatory Bowel Disease Treatment.
Mol Pharm
March 2025
Louvain Drug Research Institute, Advanced Drug Delivery and Biomaterials, UCLouvain, Université Catholique de Louvain, 1200 Brussels, Belgium.
Harnessing the effect of the cyclic GMP-AMP Synthase-STimulator of INterferon Genes (cGAS-STING) signaling pathway has emerged as a promising approach to developing novel strategies for the oral treatment of inflammatory bowel disease (IBD). In this work, we screened different cGAS-STING inhibitors in murine macrophages. Then, we encapsulated the cGAS-STING inhibitor H-151 within lipid nanocapsules (LNCs), owing to their inherent ability to induce the secretion of glucagon-like peptide 2 (GLP-2), a re-epithelizing peptide, upon oral administration.
View Article and Find Full Text PDFDietary supplementation of new-born foals with free nucleotides positively affects neonatal diarrhoea management.
Ir Vet J
March 2025
Department of Veterinary Sciences, University of Turin, Largo Braccini 2, Grugliasco, 10095, Italy.
Foals commonly experience diarrhoea in the first weeks of life. Although this condition is rarely life-threatening, it can have significant health consequences. This study investigated whether new-born foals can benefit from a dietary supplement of nucleotides, as already demonstrated in other species.
View Article and Find Full Text PDFVascular remodeling and TSLP/angiogenin overexpression in severe mixed asthma.
Respir Res
February 2025
Department of Clinical and Biological Sciences, University of Turin, Turin, TO, Italy.
Background: Asthma with neutrophilic/mixed inflammation is a difficult-to-control clinical phenotype. Currently, vascular and matrix airway remodeling in asthma with neutrophilic/mixed inflammation is not well known. We aimed to evaluate the differences in vascular/smooth muscle/matrix related asthma remodeling in eosinophilic (EOS) and mixed/neutrophilic (MIXED) bronchial phenotypes in relation to asthma severity and exacerbation frequency.
View Article and Find Full Text PDFImpact of a Short-Term Western-Style Diet and Hyperandrogenism on Adult Rhesus Macaque Ovarian Function.
F S Sci
February 2025
Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, Oregon, USA; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, USA. Electronic address:
Objective: To determine the effect of an obesogenic Western-style diet and hyperandrogenemia on ovarian outcomes.
Design: Experimental, controlled animal study SUBJECTS: Post-pubertal rhesus macaque females EXPOSURE: A Western-style diet (T+WSD: 36% fat, 45% carbohydrate, 18% protein) combined with exogenously administered testosterone versus a standard chow diet (Control, CTRL; 15% fat, 59% carbohydrate, 27% protein). Animals underwent controlled ovarian stimulations to assess ovarian follicle development.
Causal associations between scapular morphology and shoulder condition estimated with Bayesian statistics.
Comput Methods Programs Biomed
February 2025
Laboratory of Biomechanical Orthopedics, Ecole Polytechnique Fédérale de Lausanne, Institute of Bioengineering, Switzerland; Service of Orthopedics and Traumatology, Lausanne University Hospital and University of Lausanne, Switzerland. Electronic address:
Background And Objective: While there is a reported correlation between shoulder condition and scapular morphology, the precise impact of typical anatomical variables remains a subject of ongoing debate. This study aimed to evaluate this causal association, by emphasizing the importance of scientific modeling before statistical analysis.
Methods: We examined the effect of scapular anatomy on shoulder condition, and conditioning on sex, age, height, and weight.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!