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Split-brain patients: A clinical vs experimental perspective.
Handb Clin Neurol
March 2025
Department of Psychological and Brain Sciences, University of California, Santa Barbara, CA, United States. Electronic address:
For more than 80 years, the clinical perspective on the behavioral outcome of split-brain surgery suggested that it "may be carried out without any untoward effect on the patient," despite some initial and transient disconnection effects. The last 60 years of experimental studies, however, have shown quite the opposite. Using lateralized testing procedures, split-brain patients have demonstrated profound disconnection effects that can last a lifetime.
View Article and Find Full Text PDFCulturally adapted developmental outcome measure for Aboriginal and Torres Strait Islander children: study protocol for the validation of the ASQ-STEPS.
BMJ Open
March 2025
Department of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia.
Introduction: Early childhood education and intervention programmes can improve the developmental outcomes for priority groups of children. However, in Australia, a culturally responsive developmental outcome measure that has been validated for use with Aboriginal and Torres Strait Islander children is required to effectively evaluate impact.The Ages and Stages Questionnaire-Steps for Measuring Aboriginal Child Development (ASQ-STEPS) has been developed to fill this gap.
View Article and Find Full Text PDFPatient experience and primary care teams: a cross-sectional survey of French elderly patients.
BMJ Open
March 2025
Department of Primary Care Federative, Nantes Universite, Nantes, France.
Objective: To assess whether patient experience is better for patients followed in a primary care team (PCT) than for patients with traditional follow-up in usual care.
Design: A cross-sectional survey based on a self-administered questionnaire.
Setting: Pays de la Loire geographical area (located on the French west coast).
The Impact of Denying Abortion Access to Patients with Chronic Kidney Disease: a cost-effectiveness analysis.
Contraception
March 2025
Oregon Health and Science University 3181 SW Sam Jackson Park Rd, Portland, OR 97239 USA. Electronic address:
Objectives: The current study focuses on how abortion access affects people who are pregnant, have chronic kidney disease (CKD), and desire an abortion. From the perspective of the pregnant patient, we will examine the outcomes and costs associated with providing or refusing in-state access to abortion for this population.
Study Design: A decision-analytic model was built to compare the outcomes and costs associated with providing abortions in-state compared to those associated with a complete statewide abortion ban.
IUPHAR Review - Novel therapeutic targets for schizophrenia treatment: a translational perspective.
Pharmacol Res
March 2025
Biological Psychiatry Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Via Pilastroni 4, 25125 Brescia, Italy; Department of Pharmacological and Biomolecular Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy. Electronic address:
Schizophrenia is a severe and debilitating psychiatric disorder that profoundly impacts cognitive, emotional, and social functioning. Despite its devastating personal and societal toll, current treatments often provide only partial relief, underscoring the urgent need for innovative therapeutic strategies. This review explores emerging approaches that target the complex neurobiological underpinnings of schizophrenia, moving beyond traditional dopamine-centric models.
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