The therapeutic community (TC) is a social-learning treatment program for people with substance use disorders (PSUDs). Most studies focused on how the TC program facilitates positive recovery outcomes. Less emphasis was given to ethnically relevant patient dispositions that may influence the TC process from a collectivist context, especially from Asian developing countries like the Philippines. In this study, we tested the TC process experience's (TCPE) path to recovery capital (RC) and psychological well-being (PWB) as mediated by group working alliance (GWA). We also examined if PSUDs' locus-of-hope (LOH), or the person's goal-pursuit disposition involving external co-agencies like peers, family, and spirit, interact with this mechanism. A total of 451 male PSUDs from TC facilities in the Philippines were surveyed, with 406 participants included in the final analysis. Results showed that the participants' TCPE predicted RC and PWB. The direct pathways were mediated by GWA. There were no significant mediation effects among patients with high internal and external-peer LOH. Moreover, there were significant mediation effects among patients with high external-family and external-spirit LOH. The results suggest the contributions of PSUDs' LOH dispositions to the TC mechanism from a collectivist population, thus revealing nuances of the TC model applied in a vulnerable ethnic context.
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http://dx.doi.org/10.1080/15332640.2025.2468295 | DOI Listing |
Ann Oncol
February 2025
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy. Electronic address:
Background: We predicted the number of cancer deaths and rates for 2025 in the European Union (EU), its five most populous countries, and the UK, focusing on breast cancer.
Materials And Methods: We derived population data and death certificates for all cancers and major sites for the EU, France, Germany, Italy, Poland, Spain, and the UK since 1970, from the World Health Organization and United Nations databases. Estimates for 2025 were computed by linear regression on recent trends identified through Poisson joinpoint regression, considering the slope of the most recent trend segment.
J Infus Nurs
March 2025
Author Affiliations: Takeda Development Center Americas, Inc., Cambridge, Massachusetts (Kim Duff); IQVIA Clinical Research Organization, Milan, Italy (Arianna Soresini); IQVIA Clinical Research Organization, Cambridge, Massachusetts (Nancy Wolf* and Alane Fairchild); IQVIA Clinical Research Organization, Ankara, Turkey (Şükran Altan**); IQVIA Clinical Research Organization, Mexico City, Mexico (Wendy Bencomo); University Clinical Center of Serbia, Belgrade, Serbia (Ivana Ivankovic); University Health Network, University of Toronto, Toronto, Ontario, Canada (Evelyn Sarpong); IQVIA Clinical Research Organization, Warsaw, Poland (Anna Kuczkowska).
Hyaluronidase-facilitated subcutaneous immunoglobulin (fSCIG) 10% offers potential improvements in patient independence and tolerability versus intravenous immunoglobulin (IVIG) when used for the treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). fSCIG 10% also requires less frequent infusions and fewer infusion sites than conventional subcutaneous immunoglobulin (subcutaneous immunoglobulin without hyaluronidase). The ADVANCE-CIDP 1 study demonstrated fSCIG 10% efficacy and safety in preventing CIDP relapse and positive responses from patients in terms of satisfaction and treatment preference.
View Article and Find Full Text PDFJ Opioid Manag
March 2025
Department of Emergency Medicine, Baylor Scott and White All Saints Medical Center, Fort Worth, Texas.
Objective: To investigate the potential impact of implementing alternatives to opioids (ALTOs) protocol in a community emergency department (ED) in North Texas. We hypothesize that the ALTO protocol is associated with decreased opioid utilization without affecting patient satisfaction to pain control and ED flow.
Design: A retrospective, single-center, cohort study.
J Opioid Manag
March 2025
Department of Surgery, Baylor University Medical Center, Dallas, Texas.
Background: The United States (US) is facing an opioid epidemic. Prescribed opioids are a contributor to this national issue. Strategies to reduce opioid prescriptions are a high priority.
View Article and Find Full Text PDFJ Opioid Manag
March 2025
Abt Global, LLC, Cambridge, Mas-sachusetts. ORCID: https://orcid.org/0000-0003-3391-2041.
Objective: The Six Building Blocks: A Team-Based Approach to Improving Opioid Management in Primary Care (6BBs) program provides a roadmap for improving the management of patients on opioid therapy for chronic pain. The goal of this project was to evaluate the How-to-Implement Toolkit (Toolkit) for clinics to independently implement the 6BBs without a practice facilitator.
Methods: Eight healthcare organizations with 62 clinics participated in the program.
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