Introduction: Focal vibration therapy (FVT) is increasingly used in the treatment of spastic paresis. In adults, it has been shown to reduce spasticity and to increase torque production from the vibrated muscles by restoring reciprocal inhibition of antagonists, thereby improving overall gait. In children with spastic cerebral palsy (CP), FVT has also been suggested to reduce spasticity, increase torque production and improve gait function, but evidence is limited.
Methods: We report the case of a child with unilateral spastic CP (USCP) and equinus gait (GFMCS II level) with (i) ankle dorsiflexor paresis, (ii) ankle plantar flexor overactivity, especially in gastrosoleus complex and peroneus longus, (iii) spastic myopathy, affecting gastrosoleus complex in particular, and (iv) calf pain seemingly related to muscle overactivity. The child was treated with a two-month program of alternating dorsiflexor and plantar flexor focal vibration therapy (FVT) and botulinum neurotoxin A (BoNT-A) injections into plantar flexors, alongside conventional physiotherapy.
Results And Discussion: Clinical evaluations during the two-month program showed (i) improved walking speed (ii) decreased ankle dorsiflexor paresis and ankle plantar flexor overactivity, especially spastic co-contraction and spasticity, (iii) improved passive extensibility in plantar flexors, and (iv) reduced pain. This is the first report of the combination of FVT and BoNT-A injections having promising effects on equinus gait in USCP.
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http://dx.doi.org/10.3389/fresc.2025.1454109 | DOI Listing |
Physiother Theory Pract
March 2025
Physiotherapy Unit, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Background: The association of different sensory inputs enhances brain plasticity in patients after stroke, but no studies have associated Action Observation Training (AOT) delivered in immersive virtual reality (VR) with Focal Vibration (FV) to elicit a kinesthetic illusion coherent with the observed task to improve motor function.
Objective: The study aimed to evaluate the feasibility of AOT delivered in immersive VR integrated with FV of upper limb muscles on manual dexterity in patients with chronic stroke.
Methods: A single-subject study was conducted (A-B design).
Int J Numer Method Biomed Eng
March 2025
School of Aerospace Engineering, Tsinghua University, Beijing, People's Republic of China.
Myringoplasty is most commonly used to treat tympanic membrane (TM) perforation. Clinical data have shown that unexplained high-frequency (above 3 kHz) hearing loss often occurs after myringoplasty. In this paper, a finite element (FE) model of the partial external and middle ear (ME) of the human ear, which considers the actual perforation and TM implants, is developed to reveal the mechanical mechanism of high-frequency hearing loss after implantation of temporalis fascia and cartilage commonly used in myringoplasty.
View Article and Find Full Text PDFJ Phys Condens Matter
March 2025
Department of Physics, Indian Institute of Technology (BHU) Varanasi Department of Physics, Dept of Physics, IIT (BHU), Varanasi-221005, India, Varanasi, UP, 221005, INDIA.
Lead-free perovskite halide CsSnI_{3} has emerged as a promising material for optoelectronic applications due to its direct bandgap (1.3-1.4 eV), high charge carrier mobility, and strong visible-spectrum absorption.
View Article and Find Full Text PDFJ Chem Theory Comput
March 2025
Academic Unit of Cabo de Santo Agostinho, Federal Rural University of Pernambuco (UFRPE), Cabo de Santo Agostinho, 54518-430, Brazil.
Understanding the dynamics of photophysical processes in Ln complexes remains challenging due to the intricate nature involving the metallic center, where sensitization (antenna effect) plays a pivotal role. Current studies have often overlooked the vibronic coupling within the antenna effect, leading to incomplete insights into excited-state dynamics. To address these shortcomings, we introduce a novel theoretical and computational approach that leverages the impact of the vibrational modes of the S and T states in this effect through the correlation function formalism, offering a comprehensive view of intersystem crossing (ISC).
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