Late gadolinium enhanced-cardiac magnetic resonance (LGE-CMR) images play a critical role in evaluating cardiac pathology, where scar tissue serves as a vital indicator impacting prognosis and treatment decisions. However, accurately segmenting scar tissues and assessing their severity present challenges due to complex tissue composition and imaging artifacts. Existing methods often lack precision and robustness, limiting their clinical applicability. This work proposes a novel methodology that integrates the optimal segmentation algorithm (OSA) for segmentation and Flamingo Gannet search optimization-enabled hybrid deep residual convolutional network (FGSO-HDResC-Net) for severity classification of scar tissues in LGE-CMR images. Initially, the input image is pre-processed by using the adaptive Gabor Kuwahara filter. Then, the approach combines myocardium segmentation via region-based convolutional neural network and scar segmentation using OSA. Subsequently, FGSO-HDResC-Net integrates feature extraction and classification while optimizing hyperparameters through Flamingo Gannet search optimization. The feature extraction stage introduces two sets of techniques: localization features with texture analysis and spatial/temporal features using a deep residual network, complemented by feature fusion using the fractional concept. These features are inputted into a customized 1D convolutional neural network model for severity classification. Through comprehensive evaluation, the effectiveness of FGSO-HDResC-Net in accurately classifying scar tissue severity is demonstrated, offering improved disease assessment and treatment planning for cardiac patients. Moreover, the proposed FGSO-HDResC-Net model demonstrated superior performance, achieving an accuracy of 96.45%, a true positive rate of 95.42%, a true negative rate of 96.48%, a positive predictive value of 94.20%, and a negative predictive value of 94.18%. The accuracy of the devised model is 14.50%, 12.99%, 10.74%, 9.75%, 12.79%, and 11.26% improved than the traditional models.
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http://dx.doi.org/10.1007/s13755-025-00340-y | DOI Listing |
Endokrynol Pol
March 2025
Department of Anaesthesiology and Intensive Therapy, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland.
Introduction: Proven risk factors for thyroid orbitopathy (TO) are thyroid dysfunction, smoking, and high levels of thyrotropin receptor antibodies (TRAb), and the role of insulin-like growth factor 1 (IGF-1), the receptor for IGF-1 (IGF-1R), and antibodies to the receptor for IGF-1 (IGF-1RAb) are also debated. IGF-1R is overexpressed in fibroblasts and orbital lymphocytes in TO patients. It forms a functional complex and mediates signal transduction through thyroid stimulating hormone receptor (TSHR).
View Article and Find Full Text PDFJ Med Microbiol
March 2025
Vaccine Preventable Bacterial Diseases, Science, Reference and Surveillance Directorate, National Microbiology Laboratory Branch, Pubic Health Agency of Canada, Winnipeg, Manitoba, Canada.
Invasive meningococcal disease (IMD) is a nationally notifiable illness in Canada due to its potential severity and transmissibility. Vaccination strategies differ by province/territory and are informed by changes in the antigenic characteristics of circulating strains. Though IMD statistics are tracked at a provincial/territorial level, there is a lack of published data characterizing trends in the epidemiology of this disease at a national level.
View Article and Find Full Text PDFCureus
February 2025
Department of Respiratory Medicine, Uttar Pradesh University of Medical Sciences, Etawah, IND.
Background Chronic obstructive pulmonary disease (COPD) results from chronic inflammation triggered by various risk factors. This inflammation can also impact other organ systems. COPD patients often have comorbidities such as osteoporosis and metabolic syndrome.
View Article and Find Full Text PDFPostep Psychiatr Neurol
December 2024
Laboratory of Human Metabolism Research, Department of Dietetics, Institute of Human Nutrition Sciences, Warsaw University of Life Science, Poland Abstract.
Purpose: Young adults experience high stress levels, leading to mood disorders. This study investigates the associations between specific fatty acid levels, lipid profiles, inflammatory markers, and emotional well-being among young adults.
Methods: Seventy-two young adults aged 18-35 participated in this study.
Pol J Radiol
January 2025
Chair of Radiology, Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland.
The aim of this paper is to present the currently used classification of split cord malformation. Split cord malformation (SCM) is a developmental defect arising during neurulation, resulting in abnormal neural tube development, with the formation of a division within the spinal cord and dural sac. The terms diastematomyelia and diplomyelia are used in the literature to describe this defect.
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