Introduction: Pseudoaneurysm following gynecologic cancer surgery is a rare complication that can become fatal when it ruptures. Common sites of pseudoaneurysms are the external iliac artery, hypogastric artery, and aorta, which are located around the lymphadenectomy site. There are no previous reports of ruptured inferior epigastric (IEA) artery pseudoaneurysms after gynecologic cancer surgery. We report a case of intraperitoneal bleeding induced by a ruptured IEA pseudoaneurysm following interval debulking surgery for stage IVB ovarian cancer.
Case Presentation: The patient underwent total abdominal simple hysterectomy, bilateral salpingo-oophorectomy, omentectomy, ileocolic resection, and peritonectomy around the ileocecal area after 5 cycles of neoadjuvant chemotherapy. The patient suddenly presented with loss of consciousness and reduced blood pressure on postoperative day 20. Her blood hemoglobin levels also decreased. Contrast-enhanced computed tomography revealed a pseudoaneurysm in the right IEA. There were no signs of extravasation from the pseudoaneurysm; however, bloody ascites was observed in the abdominal cavity. A ruptured IEA pseudoaneurysm was suspected, and coil embolization was immediately performed. Her symptoms abated soon after coil embolization, and she remained symptom-free during the 8 months of postoperative follow-up.
Conclusion: Awareness of this rare complication is clinically important for its early detection and treatment.
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http://dx.doi.org/10.1159/000543127 | DOI Listing |
World J Gastrointest Surg
February 2025
Gastric Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Background: Gastric cancer is the fifth most common cancer and the fourth leading cause of death worldwide. Most cases of newly diagnosed gastric cancer involve not only locally advanced tumor growth and regional lymph node metastases but also distant metastases. We report a rare case finding of a mass in the right inguinal area which is derived from gastric cancer.
View Article and Find Full Text PDFNeurocrit Care
March 2025
Department of Intensive Care Unit, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Background: The C3a/C3aR axis has been shown to play an important role in a variety of neurological diseases. The aim of this study was to investigate the effects of the C3aR antagonist SB290157 on neuroinflammation in a mouse model of intracerebral hemorrhage (ICH) and the mechanism of the protein kinase C (PKC)/P38/NLRP3 signaling pathway in C3aR-mediated neuroinflammation.
Methods: A total of 276 CD-1 mice were randomly assigned to different experimental groups.
J Curr Ophthalmol
January 2025
Department of Physiology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey.
Purpose: To investigate the neuroprotective effect of riluzole through matrix metalloproteinase-2 (MMP-2) and MMP-9 in rats, in an experimental glaucoma model.
Methods: A total of 28 rats, 3-4 months old, weighing 250-300 g, were divided into four groups; Group I (control), Group II (glaucoma), Group III (glaucoma + corn oil + dimethyl sulfoxide (DMSO), and Group IV (glaucoma + corn oil + DMSO + riluzole). A glaucoma model was created by episcleral vein cauterization in the left eyes of Group II, III, and IV subjects.
BMC Anesthesiol
February 2025
Department of Anesthesiology, Second Affiliated Hospital of Kunming Medical University, No. 374 of Dianmian Road, Wuhua District, Kunming, 650101, China.
Objective: The objective of this study was to investigate the efficacy and safety of tranexamic acid (TXA) in hepatectomy when administered as per the standardized protocol of controlled low central venous pressure (CLCVP).
Methods: This study was a randomized, double-blind, controlled study. Patients who fulfilled the inclusion criteria were randomly assigned to the TXA group (group T) or the placebo group (group N).
Life Sci
April 2025
Tianjin Neurological Institute, Key Laboratory of Post-Neuro injury, Neuro-repair and Regeneration in Central Nervous System, Ministry of Education and Tianjin City, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, China; Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China; State Key Laboratory of Experimental Hematology, Tianjin, China. Electronic address:
Aims: Traumatic brain injury-induced coagulopathy (TBI-IC) frequently occurs after TBI, exacerbating the severity of TBI and affecting patient prognosis. Benzbromarone (BBR) is commonly used to treat hyperuricemia; however, its protective effects against TBI-IC remain unknown. Therefore, we explored whether BBR could improve TBI.
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