Introduction: Liposarcoma, one of the most common soft tissue sarcomas, originates from primitive mesenchymal cells. However, spinal involvement of liposarcoma, whether primary or metastatic, is rare. According to literature reports, myxoid/round cell liposarcomas are the most common types affecting the spine. Spinal liposarcomas, whether primary or metastatic, have only been sporadically reported.
Case Presentation: The author presents an unusual case of recurrent myxoid liposarcoma originating from the erector spinae muscle, infiltrating the upper thoracic spine in a 65-year-old female. The patient presented with a 1-week history of progressively worsening right chest and back pain. The treatment approach involved surgical intervention with wide tumor resection, spinal cord decompression, posterior instrumentation, and thoracoplasty, complemented by radiotherapy.
Conclusion: The preferred treatment is en bloc resection with wide margins. Postoperative radiation therapy can serve as complementary treatment for piecemeal resection. A follow-up is necessary because of the potential for recurrence.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723665 | PMC |
http://dx.doi.org/10.1159/000542503 | DOI Listing |
Cureus
February 2025
Department of Plastic Surgery, Dermatology and Plastic Surgery of Arizona, Tucson, USA.
Chondroid syringomas are rare adnexal neoplasms composed of epithelial and mesenchymal components, posing diagnostic challenges due to their diverse histological features. We report an atypical presentation of an apocrine mixed tumor in a 51-year-old female patient who presented with a 0.7 cm firm, flesh-colored nodule on the right lateral cutaneous lip.
View Article and Find Full Text PDFFront Cardiovasc Med
February 2025
Department of Pathology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Background: Intimal Sarcoma (IS) is an exceptionally rare and highly aggressive mesenchymal tumor with an uncertain origin. Its clinical and pathological characteristics are challenging to differentiate from other tumors based merely on histological and cytological morphology. Additionally, the immunohistochemical phenotype lacks specificity.
View Article and Find Full Text PDFActa Otolaryngol
February 2025
Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic Florida, Jacksonville, FL, USA.
Background: Parapharyngeal space liposarcomas (PPS-LS) are rare tumors often associated with a moderate-to-poor prognosis.
Objectives: This study aims to assess tumor control and survival outcomes across the various subtypes of PPS-LS.
Material And Methods: We conducted a systematic review of cases using PubMed, OVID, Scopus, Web of Science, ScienceDirect, and EBSCO from inception to October 2024.
Case Rep Oncol
January 2025
Orthopedics Department, Cancer Hospital of Shantou University Medical College, Shantou, China.
Introduction: Liposarcoma, one of the most common soft tissue sarcomas, originates from primitive mesenchymal cells. However, spinal involvement of liposarcoma, whether primary or metastatic, is rare. According to literature reports, myxoid/round cell liposarcomas are the most common types affecting the spine.
View Article and Find Full Text PDFCancer Med
February 2025
Department of Plastic and Hand Surgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Background: Myxoid liposarcomas (MLS) can exhibit a disseminated metastatic pattern, necessitating extensive diagnostics during follow-up. With no tumor markers available, early diagnosis of recurrences and tumor monitoring is difficult. The detection of circulating tumor DNA (ctDNA; liquid biopsy) in MLS with the characteristic translocations t(12;16) and t(12;22) can provide an additional diagnostic.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!