Background: Total hip arthroplasty is a common surgical procedure used to reduce pain and improve hip joint function in patients with advanced hip inflammation. Patient-controlled epidural analgesia is more effective in reducing postoperative anxiety. In addition, combined spinal and epidural anesthesia is associated with a lower incidence of respiratory complications like atelectasis. This retrospective comaprative study compared the post operative analgesic effect and postoperative recovery of intravenous patient-controlled analgesia and patient-controlled epidural analgesia.

Methods: A total of 200 patients received hip arthroplasty from January 2018 to January 2021. The patients were divided into the study group (patient-controlled epidural analgesia group, N = 110) and the control group (intravenous patient-controlled analgesia group, N = 90). Various factors were examined, including the surgical procedure, Ramsay Sedation Scale (RSS), resting visual analogue scale (VAS), Bruggrmann comfort scale (BCS), postoperative recovery, and the prevalence of postoperative adverse reactions.

Results: The study group showed statistically significant shorter operation time, respiratory recovery time, eye opening time, extubation time, and orientation recovery time, lower RSS score at 4 h, 8 h, 12 h, 24 h, and 48 h compared to the control group. Similarly, the VAS score in the study group was significantly lower at the same time points after operation. Moreover, the BCS scores in the study group were significantly higher at the same time points after operation. The study group demonstrated statistically significant higher comfort levels and shorter times for first mobilization, first bowel movement, and length of hospital stay compared to the control group. Only four cases in the study group experienced nausea and vomiting, somnolence, dizziness, and respiratory depression, while 13 cases in the control group experienced nausea and vomiting, rash, lower limb fatigue, hypotension, drowsiness, dizziness, postoperative mental disorder, and respiratory depression.

Conclusion: The results reveal that patient-controlled epidural analgesia offers superior pain relief, lower side effects, better post-operative analgesic effect, and better postoperative recovery. Patient-controlled epidural analgesia shows great promising clinical application potential for anesthesia after total hip arthroplasty.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11841313PMC
http://dx.doi.org/10.1186/s12871-025-02931-4DOI Listing

Publication Analysis

Top Keywords

study group
24
patient-controlled epidural
20
hip arthroplasty
16
epidural analgesia
16
control group
16
intravenous patient-controlled
12
patient-controlled analgesia
12
total hip
12
postoperative recovery
12
group
12

Similar Publications

Community-acquired pneumonia (CAP) has a significant impact on public health, especially in light of the recent SARS-CoV-2 pandemic. To enhance disease characterization and improve understanding of the underlying mechanisms, a comprehensive analysis of the plasma lipidome, metabolome and proteome was conducted in patients with viral and bacterial CAP infections, including those induced by SARS-CoV-2. Lipidomic, metabolomic and proteomic profiling were conducted on plasma samples of 69 patients suffering either from viral or bacterial CAP.

View Article and Find Full Text PDF

Introduction: Linezolid is a broadly used antibiotic to treat complicated infections caused by gram-positive bacteria. Therapeutic drug monitoring of linezolid concentrations is recommended to maximise its efficacy and safety, mainly haematological toxicity. Different pharmacokinetic/pharmacodynamic targets have been proposed to improve linezolid exposure: the ratio of the area under the concentration-time curve during a 24-hour period to minimum inhibitory concentration (MIC) between 80 and 120; percentage of time that the drug concentration remains above the MIC during a dosing interval greater than 85% and the trough concentration between 2 and 7 mg/L.

View Article and Find Full Text PDF

Our study investigates the post-mortem findings of the diaphragm's muscular structural changes in mechanically ventilated COVID-19 patients. Diaphragm samples of the right side from 42 COVID-19 critically ill patients were analyzed and correlated with the type and length of mechanical ventilation (MV), ventilatory parameters, prone positioning, and use of sedative drugs. The mean number of fibers was 550±626.

View Article and Find Full Text PDF

Dexamethasone treatment for COVID-19 is related to increased mortality in hematologic malignancy patients: results from the EPICOVIDEHA registry.

Haematologica

August 2024

Miloš Mladenović, ;Charlotte Flasshove, Bojana Mišković, ;José-María Ribera-Santasusana, Martin Hoenigl, Juergen Prattes, Malgorzata Mikulska, Annarosa Cuccaro, Emel Bekirova, Josip Batinić, ;Nick De Jonge, Tatjana Adžić-Vukičević, ;Ľuboš Drgoňa, Hans Martin Orth, Florian Reizine, Monica Piedimonte, Jörg Schubert, Andrés Soto-Silva, Jorge Loureiro-Amigo, Laura Serrano, Lisset Lorenzo De La Peña, Anna Guidetti, Irati Ormazabal-Vélez, Sandra Malak, Maria Calbacho, Noemí Fernández, Rafael F. Duarte, Elizabeth De Kort, Guldane Cengiz Seval, Luisa Verga, Rui Bergantim, María-Josefa Jiménez-Lorenzo, Johan Maertens, Nina Khanna, Matthias Egger, Omar-Francisco Coronel-Ayala, Przemyslaw Zdziarski, Alessandro Busca, Elena Busch, Christian Bjørn Poulsen, François Danion, Tania Cushion, Sergio Pinzón, Yung Gonzaga, Austin Kulasekararaj, Hossein Zarrinfar, Baerbel Hoell-Neugebauer, Chi Shan Kho, Rémy Duléry, Martin Kolditz, Monica Fung, Alina Daniela Tanase.

View Article and Find Full Text PDF

Background: In some cases of patients with out-of-hospital cardiac arrest (OHCA) who underwent extracorporeal cardiopulmonary resuscitation (ECPR), negative pupillary light reflex (PLR) and mydriasis upon hospital arrival serve as common early indicator of poor prognosis. However, in certain patients with poor prognoses inferred by pupil findings upon hospital arrival, pupillary findings improve before and after the establishment of ECPR. The association between these changes in pupillary findings and prognosis remains unclear.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!