Planning the future relies on the ability to remember how long events last, yet how durations are stored in memory is unknown. Here, we developed a novel to assess whether elapsed time is stored as a continuous feature or as a discrete item in memory. In three experiments ( = 58), participants were presented with nonisochronous sequences composed of empty time intervals delimited by brief tones. Time intervals varied in number and in duration. Participants had to reproduce as precisely as possible the duration of all time intervals in the sequence following a delay period. We manipulated the number of time intervals (-item) and the sequence duration to separate their effects on recall precision. In all three experiments, the precision of recall decreased with the number of items in the sequence, showing that durations can be stored as discrete items in working memory. Our analyses emphasize the distinction between reproduction biases that are captured by relative reproduction and decreased precision which indexes working memory load. Future research is needed to spell out the conditions under which durations are fully abstracted in working memory. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
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Int J Surg
March 2025
Centre for Screen-Based Medical Simulation, Royal Free Hospital, London, UK.
Background: An increasing number of surgical trainees are taking time out of clinical training for research, parental leave or other interests. A comprehensive review was carried out to evaluate the current evidence on whether and how such time results in surgical skill decay.
Methods: A PubMed, Embase, Web of Science, and Cochrane Library search was performed using the phrase: ("skills decay" OR "skills fade") AND "surgery.
PLoS Negl Trop Dis
March 2025
Microbial Biotechnology and Protein Research Laboratory, Department of Molecular Biology and Biotechnology, School of Sciences, Tezpur University, Tezpur, Assam, India.
Background: Venomous or dry bites can result from snake envenomation. Therefore, developing a detection test for venomous snakebites in envenomed patients can prevented from unnecessary antivenom therapy for dry bites, thereby, saving them from adverse effects and cost of antivenom therapy.
Methodology: This study demonstrates a method for the diagnosis of medically significant 'Big Four' Indian snake venoms (Naja naja, Bungarus caeruleus, Daboia russelii, Echis carinatus) in the plasma of experimentally envenomed animals (envenomed under laboratory conditions).
Background: Tiredness/fatigue is a common presenting complaint. Advice is available from the National Institute for Health and Care Excellence (NICE) Clinical Knowledge Summary (CKS) on its investigation. The application of this guidance has not been reported.
View Article and Find Full Text PDFSports Med
March 2025
Department of Evolutionary Anthropology, Duke University, Durham, NC, USA.
Background: Dietary nitrate (NO) supplementation is purported to benefit exercise performance. However, previous studies have evaluated this nutritional strategy with various performance outcomes, exercise tasks, and dosing regimens, often yielding inconsistent results that limit the generalizability of the findings.
Objective: We aimed to synthesize the available evidence regarding the effect of NO supplementation on 11 domains of exercise performance.
J Anal Toxicol
March 2025
Department of Forensic Genetics and Forensic Toxicology, National Board of Forensic Medicine, Artillerigatan 12, Linköping 587 58, Sweden.
Phosphatidylethanol (PEth) consists of phospholipids synthesized in erythrocyte cell membranes in the presence of ethanol and serves as a sensitive and specific indicator of alcohol consumption. Further research on PEth formation, degradation, and stability in postmortem (PM) samples would support its routine application in forensic toxicology. A supercritical fluid chromatography-tandem mass spectrometry (SFC-MS/MS) method was developed and validated to quantify PEth 16:0/18:1 in blood.
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