Background: Ethiopia is one of the countries with the highest burden of neglected tropical diseases (NTDs), with 16 of 20 recognised NTDs considered a public health problem, twelve of which have been identified as public health priorities by the Ethiopian Federal Ministry of Health. However, until recently NTDs have not received adequate attention at national and subnational levels in the country. This study assessed feasibility, acceptability, and cost-effectiveness of an NTD intervention when integrated into the primary health care system in Ethiopia.
Methods: This study was conducted in Damot Gale district, Wolaita Zone, Southern Ethiopia and used a mixed methods approach to evaluate an intervention integrating four common NTDs (trachoma, lymphatic filariasis, schistosomiasis and podoconiosis) into Ethiopia's primary healthcare system. The intervention consisted of adapted job aids, supportive supervision, and improved supplies of medical tools to improve diagnosis, management and reporting.
Results: The study found that the intervention was feasible and successful at improving the detection, management and reporting across the four common NTD's included and had a high level of acceptance from health workers. The intervention demonstrated cost-effectiveness.
Conclusion: The findings highlight the need for further investment and consideration of integrating and scaling up NTD interventions at the primary healthcare level in Ethiopia, demonstrating that providing a package of interventions to support integration can be a cost-effective method.
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http://dx.doi.org/10.1371/journal.pntd.0011718 | DOI Listing |
Knee Surg Sports Traumatol Arthrosc
March 2025
Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK.
Purpose: This systematic review and meta-analysis aimed to establish the relationship between the number of procedures a hospital or surgeon performs with outcomes following revision knee replacement (RevKR).
Methods: MEDLINE and Embase were searched using Ovid silver platter up to December 2024 for randomised controlled trials and cohort studies that reported RevKR volumes, in at least two categories, performed by hospitals and surgeons and their relationship to patient and provider level outcomes. The primary outcome was re-revision rate.
Transfusion
March 2025
Israel Defense Forces Medical Corps, Surgeon General's Headquarters, Israel Defense Forces, Ramat Gan, Israel.
Background: Thoracic injuries are a leading cause of morbidity and mortality in military trauma. Tension pneumothorax (TPX) is a critical diagnosis that can lead to rapid hemodynamic and respiratory collapse if untreated. While timely intervention is essential, prehospital TPX diagnosis is challenging and may lead to unnecessary interventions.
View Article and Find Full Text PDFNutr Hosp
March 2025
Facultad de Medicina. Universidad de Castilla-La Mancha.
Introduction: currently there are changes in lifestyle that have been modifying the nutritional culture, moving away from the Mediterranean diet (DMed) and acquiring a more sedentary lifestyle, a fact that has contributed to a significant increase in risk factors. (CVRF) such as obesity and type 2 diabetes mellitus (DM2), and consequently to a global increase in metabolic syndrome (MS) and cardiovascular diseases (CVD), which in the 21st century reinforces being the first cause of morbidity and mortality To reduce this pandemic, a multidisciplinary approach is required focused on the application of primary and secondary prevention strategies for modifiable CVRFs, focused on nutritional promotion and education through the promotion of a healthier lifestyle and diet from childhood, as the one that encompasses the MedD. This dietary pattern, together with physical exercise, has been shown to contribute to the primary and secondary prevention of DM2 and coexisting CVRF.
View Article and Find Full Text PDFFront Pediatr
February 2025
Department of Primary Care, Ohio University Heritage College of Osteopathic Medicine, Athens, OH, United States.
Children with neurodevelopmental disabilities living in rural and low-resourced regions within the United States, such as Appalachia, face gaps and barriers to accessing healthcare services due to a shortage of providers, specialists, hospitals, and clinics. Without access to specialized medical and rehabilitation services, their performance across developmental domains and participation within their communities is likely suboptimal. The purpose of this study was to identify both intrinsic and extrinsic factors using a mixed-methods approach to better understand factors that may impact performance across developmental domains and participation for children with disabilities living in Appalachia.
View Article and Find Full Text PDFFront Neurol
February 2025
Department of Neurology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Background: Mobile Stroke Units (MSU) shorten time to intravenous thrombolysis (IVT) and improve functional outcome, but they rely on computed tomography (CT) making them highly specialized and costly. Alternative technologies can potentially identify imaging-based IVT contraindications like intracranial hemorrhage (ICH) or malignancies (IM), e.g.
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