This study aimed to identify the correlation between treatment adherence and spiritual well-being in patients with Type 2 Diabetes. A descriptive and correlational design was used. The study consisted of 203 patients. The data were collected through a patient information form, The Scale for Compliance to the Treatment in Type 2 Diabetes Mellitus and the FACIT-Sp-12 and analyzed by using descriptive and Pearson's Correlation analysis. A correlation was found between patients treatment adherence and their peace, faith, and meaning sub-dimensions of the FACIT Sp-12. This study shows a need for interventions for patients with Type 2 diabetes to increase their spiritual well-being and, therefore, their treatment adherence. For this reason, individuals' needs should be met with a holistic approach by integrating spiritual care into nursing care practices.
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