Chronic expanding hematoma is a hematoma that gradually increases in size over a period. Only a few studies reported a chronic expanding hematoma that turned into a malignancy, we report a rare presentation of a chronically expanding hematoma that after 10 years became an angiosarcoma. This is a 41-year-old gentleman, presented to our Emergency Department, complaining of left upper gluteal pain and bleeding after he underwent hematoma evacuation in a private hospital. The patient was then admitted for infected hematoma evacuation. The patient tolerated the surgery; however, there was a persistent drop of hemoglobin postoperatively. All pathology and culture results were inconclusive. We then proceeded with computer tomography angiogram, which came back negative. Magnetic resonance imaging was then requested, which came with a slight interval change and a suspicious area, and so interventional radiology was involved to take a biopsy, which came back as angiosarcoma and then the patient underwent wide local excision with reconstruction.
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http://dx.doi.org/10.1093/jscr/rjaf063 | DOI Listing |
Semin Fetal Neonatal Med
March 2025
Department of Obstetrics and Gynecology, Intermountain Health, Murray, UT, USA; Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, UT, USA. Electronic address:
Iron deficiency is a highly prevalent nutritional deficiency and the most common cause of anemia worldwide. Pregnant individuals are particularly susceptible due to increased demands to support expanding maternal blood volume and fetal growth. Iron deficiency and iron deficiency anemia are associated with maternal and neonatal morbidity, including preterm birth, preeclampsia, postpartum hemorrhage, and low birth weight.
View Article and Find Full Text PDFZhong Nan Da Xue Xue Bao Yi Xue Ban
October 2024
Department of Ophthalmology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Objectives: Due to the severe shortage of donor corneas for transplantation in China, corneal component transplantation may expand the available donor pool. This study aims to evaluate the safety and feasibility of corneal component transplantation by examining the distribution of hepatitis B surface antigen (HBsAg) in corneas from HBsAg-seropositive donors under different storage media.
Methods: Ten corneas (from 6 donors) donated between December 2019 and March 2021 and stored at the Eye Bank of Xiangya Third Hospital, Central South University, were analyzed.
J Immunol
January 2025
Center for Translational Immunology, Benaroya Research Institute, Seattle, WA, United States.
The CD2-depleting drug alefacept (LFA3-Ig) preserved beta cell function in new-onset type 1 diabetes (T1D) patients. The most promising biomarkers of response were late expansion of exhausted CD8 T cells and rare baseline inflammatory islet-reactive CD4 T cells, neither of which can be used to measure responses to drug in the weeks after treatment. Thus, we investigated whether early changes in T cell immunophenotypes could serve as biomarkers of drug activity.
View Article and Find Full Text PDFClin Dysmorphol
March 2025
Nottingham Clinical Genetics Service, Nottingham City Hospital.
PLoS Negl Trop Dis
March 2025
Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia, United States of America.
Trypanosoma cruzi is a single-celled eukaryotic parasite responsible for Chagas disease, a major cause of morbidity and mortality in Central and South America. While the host-pathogen interactions of T. cruzi have been extensively studied in vertebrate models, investigations into its interactions within its insect host remain limited.
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