This case study delves into an uncommon occurrence of internal root resorption (IRR), an inflammatory variant with perforation of root, in the left central incisor, which seems to have a prevalence ranging from 0.01% to 1%. The patient presented with pain in the upper left front tooth, leading to a diagnosis of pulpal necrosis with symptomatic apical periodontitis. The initial phase involved identifying the three-dimensional overview of resorption and perforation using cone-beam computed tomography and nonsurgical root canal treatment utilizing orthograde mineral trioxide aggregate (MTA) placement and thermoplasticized obturation technique, aided by sonic-irrigation, and intracanal medicament under magnification. In the later phase, based on the clinical and radiographical evaluation and addressing the complexities of the perforative resorptive lesion, surgical approach needed to be performed. A 6-month follow-up revealed the arrest of IRR and a satisfactory overall outcome. This case report discusses the etiology, prevalence, clinical decision-making, and therapeutic management of IRR.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835362 | PMC |
http://dx.doi.org/10.4103/JCDE.JCDE_433_24 | DOI Listing |
Endocr Regul
January 2025
1Endocrinology and Internal Medicine Department, Fattouma Bourguiba University Hospital, Monastir, Tunisia.
Pituitary neuroendocrine tumors (PitNETS) are common intracranial tumors, but extrasellar or ectopic PitNETS are very rare and supposed to originate from some pituitary remnants. They are mostly found in sphenoidal sinus. But particularly, ectopic clival PitNETS are highly aggressive and can cause bone invasion and can be misdiagnosed as other lesions of the skull base such as chordomas.
View Article and Find Full Text PDFPediatr Infect Dis J
March 2025
National Reference Laboratory for Plague, Tularemia and Q Fever.
Mediterranean spotted fever has recently been reported in Iran, yet it continues to be overlooked by healthcare professionals in the country. This case report details a 19-month-old child who presented with fever, edema and skin rashes and was initially misdiagnosed. Subsequent testing revealed a Mediterranean spotted fever infection through IgG seroconversion.
View Article and Find Full Text PDFN Engl J Med
March 2025
Department of Pathology, Massachusetts General Hospital, Boston.
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