Responsible AI in biotechnology: balancing discovery, innovation and biosecurity risks.

Front Bioeng Biotechnol

Department of Microbes, Infection and Microbiomes, School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, Birmingham, United Kingdom.

Published: February 2025

The integration of artificial intelligence (AI) in protein design presents unparalleled opportunities for innovation in bioengineering and biotechnology. However, it also raises significant biosecurity concerns. This review examines the changing landscape of bioweapon risks, the dual-use potential of AI-driven bioengineering tools, and the necessary safeguards to prevent misuse while fostering innovation. It highlights emerging policy frameworks, technical safeguards, and community responses aimed at mitigating risks and enabling responsible development and application of AI in protein design.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835847PMC
http://dx.doi.org/10.3389/fbioe.2025.1537471DOI Listing

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