The Learning, Executive, and Attention Functioning (LEAF) scale is a resource-friendly means of assessing executive functions (EFs) and related constructs (e.g., academic abilities) in children and adolescents that has been adapted for use with adults. However, no study in any population has investigated the factor structure of all LEAF EF items to determine whether items factor in a manner consistent with the originally proposed scale structure. Therefore, we examined LEAF scale responses of 546 young adults ( = 20.05, = 2.17). Upon removing academic items following a preliminary factor analysis, we performed principal axis factoring on the remaining 39 EF items. The final model accounted for 61.75% of the total variance in LEAF EF items and suggested that these items assess six moderately correlated EF constructs in young adults. We constructed six updated subscales to help researchers measure these EFs in young adults using the LEAF scale, each of which uniquely and differentially predicted measures of self-reported impulsivity, academic difficulties, and learning-related disorder history. Overall, the LEAF promises to be an accessible means of assessing a range of EF constructs in young adults, particularly when updated subscale structures based on factor analysis are used.
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http://dx.doi.org/10.1177/10731911251317788 | DOI Listing |
Cancer Med
March 2025
Universidad Autónoma del Estado de Morelos, Facultad de Medicina, Cuernavaca, Morelos, Mexico.
Introduction: Osteosarcoma, a highly aggressive bone cancer primarily affecting children and young adults, remains a significant challenge in clinical oncology. Metastasis stands as the primary cause of mortality in osteosarcoma patients. However, the mechanisms driving this process remain incompletely understood.
View Article and Find Full Text PDFEpidemiol Psychiatr Sci
March 2025
Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Aims: To examine the risk of perinatal mental illness, including new diagnoses and recurrent use of mental healthcare, comparing women with and without traumatic brain injury (TBI), and to identify injury-related factors associated with these outcomes among women with TBI.
Methods: We conducted a population-based cohort study in Ontario, Canada, of all obstetrical deliveries to women in 2012-2021, excluding those with mental healthcare use in the year before conception. The cohort was stratified into women with no remote mental illness history (to identify new mental illness diagnoses between conception and 365 days postpartum) and those with a remote mental illness history (to identify recurrent illnesses).
Circ Cardiovasc Imaging
March 2025
Department of Cardiology, Cardiovascular Institute, Thorax Center, Erasmus MC, Rotterdam, The Netherlands (J.J.S., N.v.d.V., D.M., A.H.).
Background: Very preterm-born infants are at risk for developing bronchopulmonary dysplasia (BPD), a chronic lung disease. Nowadays, the majority of these infants reach adulthood. Very preterm-born young adults are at risk for developing pulmonary arterial (PA) hypertension later in life.
View Article and Find Full Text PDFPsychol Med
March 2025
Wolfson Institute of Population Health, Queen Mary University of London, London, UK.
Background: Population-level preventive interventions are urgently needed and may be effective for psychosis due to social determinants. We tested three syndemic models along pathways from childhood adversity (CA) to psychotic spectrum disorder (PSD) and their implications for prevention.
Methods: Cross-sectional data from 7461 British men surveyed in 5 population subgroups.
Front Immunol
March 2025
Department of Lymphoma and Myeloma Research Center, Beijing GoBroad Hospital, Beijing, China.
Autologous stem cell transplantation (ASCT) and chimeric antigen receptor T-cells (CAR-T) have been used as consolidation therapies for patients with refractory/relapsed B cell non-Hodgkin's lymphoma (R/R B-NHL) in remission after second-line chemotherapy or salvage therapy. However, patients with different pathological subtypes and remission states may benefit differently from ASCT or CAR-T cell therapy. Furthermore, consolidation treatment involving ASCT or CAR-T cells still poses a significant risk of disease relapse.
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