Rationale: Lemierre syndrome is a rare, life-threatening complication of oropharyngeal infections.
Patient Concerns: A 35-year-old man started with an upper respiratory infection but worsened the clinical course with sepsis and acute respiratory failure with complicated bilateral pleural effusion.
Diagnoses: The patient was diagnosed with typical Lemierre syndrome with lung complications.
Interventions: Antibiotic therapy with bilateral pleural percutaneous drain with fibrinolysis.
Outcomes: The patient improved and was discharged without oxygen therapy after antibiotics were covered and active lung care with complicated parapneumonic effusion. After discharge, lung function showed restrictive lung defect but improved compared to the initial exam.
Lessons: Lemierre syndrome, which might begin as a mild upper respiratory infection, can progress to a critically ill disease accompanied by sepsis and metastatic septic embolus. The patient suffered septic lung emboli with bilateral complicated parapneumonic effusion but was successfully treated with percutaneous drainage with pleural fibrinolysis, appropriate antibiotics, and anticoagulants. Early suspicion of the disease and active treatment are necessary to treat rare syndromes like Lemierre syndrome.
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http://dx.doi.org/10.1097/MD.0000000000041102 | DOI Listing |
Ear Nose Throat J
March 2025
ENT Department, Military Hospital of Instruction of Tunis, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Lemierre's syndrome is a rare and life-threatening form of septic thrombophlebitis that can complicate head and neck infections. In most cases, septic thrombophlebitis affects the internal jugular vein. Its extension into the cerebral venous sinus is extremely rare, especially in the cavernous sinus.
View Article and Find Full Text PDFCureus
February 2025
Nephrology, Georgetown University, Washington, D.C., USA.
Lemierre's syndrome is characterized by a septic inflammatory condition involving internal jugular veins and is frequently caused by an oropharyngeal infection. While it usually results in pulmonary embolization, this case demonstrates a rare but significant cerebral embolization. The case involves an 18-year-old woman who experienced left-sided neck swelling and difficulty swallowing five days after a tooth extraction, an uncommon trigger.
View Article and Find Full Text PDFEar Nose Throat J
February 2025
Department of Radiology of the First Affiliated Hospital of Guizhou TCM University, Cuiyang, Guizhou, China.
Septic thrombophlebitis of the internal jugular vein (IJV), known as Lemierre's syndrome, is a rare complication secondary to infections in the head and neck. Cholesteatoma of the middle ear complicated with Lemierre's syndrome is rarely observed in clinical practice. Currently, the treatment controversy centers on whether anticoagulation therapy is necessary for IJV and distant metastatic emboli induced by Lemierre's syndrome.
View Article and Find Full Text PDFCureus
January 2025
Transplant Infectious Diseases, Ajmera Transplant Program, University Health Network, Toronto, CAN.
A 21-year-old woman presented with a sore throat and systemic symptoms, including fever, diarrhea, and chest pain, progressing to sepsis. Imaging revealed a pharyngeal abscess, thrombophlebitis of the left internal jugular vein, and septic emboli. Blood cultures confirmed Fusobacterium necrophorum, and the patient was diagnosed with Lemierre's syndrome.
View Article and Find Full Text PDFMedicine (Baltimore)
December 2024
Division of Pulmonary Medicine, Department of Internal Medicine, Keimyung University School of Medicine, Dongsan Hospital, Daegu, South Korea.
Rationale: Lemierre syndrome is a rare, life-threatening complication of oropharyngeal infections.
Patient Concerns: A 35-year-old man started with an upper respiratory infection but worsened the clinical course with sepsis and acute respiratory failure with complicated bilateral pleural effusion.
Diagnoses: The patient was diagnosed with typical Lemierre syndrome with lung complications.
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