[This corrects the article DOI: 10.1021/acsmedchemlett.4c00284.].
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11831370 | PMC |
| http://dx.doi.org/10.1021/acsmedchemlett.4c00617 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
5HT1R agonist alleviates presurgical prolonged sleep deprivationinduced postsurgical pain in adolescent mice.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
October 2024
Department of Anesthesiology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing 210008.
Objectives: Sleep deprivation (SD) is a risk factor for the development of chronic pain in adolescents, significantly affecting pain management and prognosis; however, the mechanisms by which SD influences postoperative pain outcomes remain unclear. This study aims to investigate the molecular mechanism through which the spinal 5-hydroxytryptamine 1 receptor (5-HT1R) regulates the excitation/inhibition (E/I) balance in the dorsal horn to modulate postoperative chronic pain induced by SD in adolescent mice.
Methods: A pain model combining 4.
Special Issue on CDS Failures: A Case Study: Optimizing CDS for Pediatric Oncology Trials by Transitioning from Interruptive to Passive Alerts.
Appl Clin Inform
March 2025
Department of Pediatrics, Division of Pediatric Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada.
Background: Many children with cancer are treated as part of interventional clinical trials. Ensuring that the correct chemotherapy treatment plan is used is paramount.
Objectives: The objectives of this report were to: (1) highlight the initial design of a clinical decision support (CDS) tool that was intended to help ensure the correct matching of research studies to research chemotherapy medications, (2) discuss the issues identified with the CDS tool, and (3) review the redesign of the tool that was done to overcome the issues identified.
Volume-targeted on high-frequency oscillatory ventilation in preterm infants: a systematic review.
J Pediatr (Rio J)
March 2025
Hospital das Clínicas de Ribeirão Preto da Universidade de São Paulo, Departamento de Pediatria, Divisão de Terapia Intensiva Neonatal, Ribeirão Preto, SP, Brazil.
Objective: This systematic review aimed to analyze, in neonates, the effects of high-frequency oscillatory ventilation (HFOV) with volume-targeted (VT) compared with conventional HFOV.
Sources: The authors searched PubMed, EMBASE, Cochrane, and ClinicalTrials.gov from inception until August 4th, 2024, to identify studies comparing HFOV with and without VT in neonates under 44 weeks corrected age.
Knee alignment and patella shape are not associated with persistence of patellofemoral pain.
J ISAKOS
March 2025
Erasmus Medical Center Rotterdam, Dr. Molewaterplein 40, 3015 GD Rotterdam. Electronic address:
Introduction: Patellofemoral pain (PFP) is suggested as a precursor of patellofemoral osteoarthritis (PFOA) later in life. This hypothesis is based on shared risk factors for both diseases, such as deviating alignment parameters. In patients with PFOA, certain 2D alignment parameters and 3D shape variations are associated with the progression of PFOA.
View Article and Find Full Text PDFUnplanned Return to the Operating Room After Cataract Surgery.
Am J Ophthalmol
March 2025
Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address:
Objective: To determine the rate of unplanned return to operation room (OR) within 90 days of cataract surgery and to identify the most common pre-operative and intraoperative risk factors.
Design: Retrospective case-control study.
Subjects And Controls: Patients aged >= 40 years undergoing cataract surgery at the Wilmer Eye Institute between 2019-2022 with at least 90 days of postoperative follow-up were included.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!